Plant base editing and prime editing: the current status and future perspectives
J Li, C Zhang, Y He, S Li, L Yan, Y Li… - Journal of Integrative …, 2023 - Wiley Online Library
Precise replacement of an allele with an elite allele controlling an important agronomic trait
in a predefined manner by gene editing technologies is highly desirable in crop …
in a predefined manner by gene editing technologies is highly desirable in crop …
[HTML][HTML] Prime editing technology and its prospects for future applications in plant biology research
HM Mahmudul, A TuskanGerald - BioDesign Research, 2020 - spj.science.org
Many applications in plant biology requires editing genomes accurately including correcting
point mutations, incorporation of single-nucleotide polymorphisms (SNPs), and introduction …
point mutations, incorporation of single-nucleotide polymorphisms (SNPs), and introduction …
Base editing in plants: applications, challenges, and future prospects
MK Azameti, WP Dauda - Frontiers in plant science, 2021 - frontiersin.org
The ability to create targeted modifications in the genomes of plants using genome editing
technologies has revolutionized research in crop improvement in the current dispensation of …
technologies has revolutionized research in crop improvement in the current dispensation of …
Base editing in crops: current advances, limitations and future implications
Targeted mutagenesis via genome‐editing technologies holds great promise in developing
improved crop varieties to meet future demands. Point mutations or single nucleotide …
improved crop varieties to meet future demands. Point mutations or single nucleotide …
Toward precision genome editing in crop plants
J Li, H Li, J Chen, L Yan, L Xia - Molecular Plant, 2020 - cell.com
Precision genome editing through homology-directed repair (HDR) in plants remains very
challenging due to the innately low occurrence of HDR and obstacles in the delivery of …
challenging due to the innately low occurrence of HDR and obstacles in the delivery of …
Development of a highly efficient prime editor 2 system in plants
J Li, L Chen, J Liang, R Xu, Y Jiang, Y Li, J Ding, M Li… - Genome biology, 2022 - Springer
Low efficiency has seriously restricted the application of prime editing (PE) systems in
plants. In this study, we develop an enhanced plant prime editor 2 system, enpPE2, by …
plants. In this study, we develop an enhanced plant prime editor 2 system, enpPE2, by …
A design optimized prime editor with expanded scope and capability in plants
W Xu, Y Yang, B Yang, CJ Krueger, Q Xiao, S Zhao… - Nature Plants, 2022 - nature.com
The ability to manipulate the genome in a programmable manner has illuminated biology
and shown promise in plant breeding. Prime editing, a versatile gene-editing approach that …
and shown promise in plant breeding. Prime editing, a versatile gene-editing approach that …
[HTML][HTML] Base editing in plants: current status and challenges
SS Bharat, S Li, J Li, L Yan, L Xia - The Crop Journal, 2020 - Elsevier
Genome editing technologies have revolutionized the field of plant science by enabling
targeted modification of plant genomes and are emerging as powerful tools for both plant …
targeted modification of plant genomes and are emerging as powerful tools for both plant …
Development of plant prime-editing systems for precise genome editing
R Xu, J Li, X Liu, T Shan, R Qin, P Wei - Plant Communications, 2020 - cell.com
Prime-editing systems have the capability to perform efficient and precise genome editing in
human cells. In this study, we first developed a plant prime editor 2 (pPE2) system and test …
human cells. In this study, we first developed a plant prime editor 2 (pPE2) system and test …
Improvement of base editors and prime editors advances precision genome engineering in plants
K Hua, P Han, JK Zhu - Plant physiology, 2022 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated
protein (Cas)-mediated gene disruption has revolutionized biomedical research as well as …
protein (Cas)-mediated gene disruption has revolutionized biomedical research as well as …