Chemokines and their receptors are a large family of inflammatory molecules responsible for
a number of biological functions, including the accumulation of leukocytes at tissue sites …

The chemokine system coordinates leukocyte migration in immunity and inflammation and is
implicated in the pathogenesis of many human diseases. Although several successful …

Chemokines are low molecular weight cytokines that induce extravasation, chemotaxis, and
activation of a wide variety of leukocytes. Members of the different chemokine families are …

Chemokines are cytokines that specifically direct the trafficking of immune cells in the body.
They offer a novel point of therapeutic intervention, as inhibiting specific chemokines and …

Inflammation plays a pivotal role in exacerbating a wide array of human diseases. The
chemokines are a group of proteins that control the movement and activation of the immune …

Chemokines play a key role in immune processes by controlling leukocyte recruitment in
physiological and pathological condition. This review discusses the regulation of the …

Chemokines are a family of low molecular weight proteins with an essential role in leukocyte
trafficking during both homeostasis and inflammation. The CC class of chemokines consists …

Chemokines and chemokine receptors form a complex and diverse system known to be
relevant for leukocyte activation and trafficking. There has been significant interest in the …

Chemokines are proinflammatory mediators that primarily control leukocyte migration into
selected tissues and upregulation of adhesion receptors. They also have a role in …

There is considerable interest in the therapeutic utility of inhibiting cellular trafficking in a
variety of inflammatory diseases. Approaches including inhibition of adhesion molecule …