The pain-signaling molecules, nitric oxide synthase (NOS) and calcitonin gene-related
peptide (CGRP), are implicated in the pathophysiology of post-traumatic headache (PTH) as …

Background Frequent mild head injuries or concussion along with the presence of
headache may contribute to the persistence of concussion symptoms. Methods In this study …

Background Acute and persistent post-traumatic headache are often debilitating
consequences of traumatic brain injury. Underlying physiological mechanisms of post …

Background. Recent animal research suggests that mild traumatic brain injury (mTBI)
facilitates abnormal endogenous modulation of pain, potentially underlying the increased …

Aim Determine the role of calcitonin-gene related peptide in promoting post-traumatic
headache and dysregulation of central pain modulation induced by mild traumatic brain …

Background Post-traumatic headache is the most common and long-lasting impairment
observed following mild traumatic brain injury, and frequently has migraine-like …

Objective.—This study tests the hypothesis that injury to the somatosensory cortex is
associated with periorbital allodynia and increases in nociceptive neuropeptides in the …

Chronic complications of traumatic brain injury represent one of the greatest financial
burdens and sources of suffering in the society today. A substantial number of these patients …

Post-traumatic headache (PTH) following TBI is a common and often persisting pain
disability. PTH is often associated with a multimodal central pain sensitization on the skin …

Background Headache is one of the most common symptoms following traumatic head
injury. The mechanisms underlying the emergence of such post‐traumatic headache (PTH) …