Sepsis is a life-threatening condition and a significant cause of preventable morbidity and
mortality globally. Among the leading causative agents of sepsis are bacterial pathogens …

Sepsis is a major health problem. The concept that sepsis mortality is the result of an
uncontrolled hyperinflammatory host response has recently been challenged. It is now …

Pathogenic sepsis is not a monolithic condition. Three major types of sepsis exist within this
category: bacterial, viral, and fungal, each with its own mechanism of action. While similar in …

2. Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence 2014; 5: 4-11;
PMID: 24335434; http://dx. doi. org/10.4161/viru. 27372 3. Angele MK, Pratschke S, Hubbard …

Sepsis is a serious condition that is associated with high mortality despite advanced modern
medical treatment. Recent years have witnessed novel paradigms describing host …

The last two to three years provided several “big steps” regarding our understanding and
management of sepsis. The increasing insight into pathomechanisms of post-infectious …

Sepsis is caused by infection, and knowing what type of organism is causing the infection
certainly matters in terms of both epidemiology and selecting antibiotic therapy. Although …

Bacteremia and sepsis are major health concerns. Despite intensive research, there are
only a limited number of successful treatment options, and it is difficult to see the forest for …

Pathophysiologic basis of sepsis: Considerations for future... : Critical Care Medicine
Pathophysiologic basis of sepsis: Considerations for future strategies of intervention : Critical …

In modern intensive care settings, gram-positive bacteria account for up to 50% of severe
sepsis or septic shock cases, yet the pathogenesis of gram-positive shock is poorly …