Piplartines are alkaloid amides present in the roots and stems of different pepper species
which have promising pharmacological properties including cancer prevention. Some recent …

In this study, we have investigated the binding affinity of the newly approved tyrosine kinase
inhibitor nintedanib (NIB) with human serum albumin under simulated physiological …

Human Serum Albumin (HSA) is a principal extracellular protein with a high concentration in
blood plasma and a carrier of many drugs to different molecular targets. Drug binding to …

The interaction of proteins with nanoparticle components are crucial for the evaluation of
nanoparticle function, toxicity and biodistribution. Polyethyleneimines (PEIs) with defined …

Protein is an important component of human tissues and cells, which is closely related to
various life activities. Therefore, studying the conformation of proteins can not only provide …

The interaction of a new heterocyclic Schiff base bearing pyridine and pyrimidine cycles,
with human serum albumin (HSA) using molecular docking and molecular dynamics …

We report the scanning probe microscope (SPM)-based single-molecule recognition of
biomolecular interactions between protein kinase and small ligands (ie, ATP and Imatinib) …

Interaction forces between biological molecules such as antigen and antibody play
important roles in many biological processes, but probing these forces remains technically …

Proteins are major drug targets, and drug–target interaction identification and analysis are
important factors for drug discovery. Atomic force microscopy (AFM) is a powerful tool …