Cardiovascular disease (CVD) remains one of the leading causes of death and disability in
developed countries around the world despite the documented success of lifestyle and …

Peripheral blood mononuclear cells (PBMCs) are a variety of specialized immune cells
produced in the bone marrow from hematopoietic stem cells (HSCs) that work together to …

Chemokines recruit inflammatory cells to sites of injury, but the role of the CC chemokine
receptor 2 (CCR2) during regenerative processes following ischemia is poorly understood …

Chemokines play a crucial role in inflammation and in the pathophysiology of
atherosclerosis by recruiting inflammatory immune cells to the endothelium. Chemokine …

Skeletal muscle is an endocrine organ that secretes several proteins, which are collectively
termed myokines. Although many studies suggest that exercise regulates myokine secretion …

Background—Atherosclerosis is a systemic inflammatory disease characterized by the
formation of atherosclerotic plaques. Both innate immunity and adaptive immunity contribute …

Various types of exercise alter the population of circulating peripheral blood mononuclear
cells (PBMCs) and change their transcriptional output. This work examines changes in …

This study sought to compare the respective effects of resistance or aerobic exercise of
higher or lower intensities on the acute plasma interleukin-6 (IL-6) and C-reactive protein …

BACKGROUND: Physical activity may lower the risk for coronary artery disease (CAD) by
mitigating inflammation, which plays a key role in the pathophysiology of atherosclerosis …

Purpose Numerous cross-sectional studies have observed an inverse association between
CRP and physical activity. Exercise-training trials have produced conflicting results, but …