[HTML][HTML] The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
Null mutations in the C. elegans heterochronic gene lin-41 cause precocious expression of
adult fates at larval stages. Increased lin-41 activity causes the opposite phenotype …
adult fates at larval stages. Increased lin-41 activity causes the opposite phenotype …
[HTML][HTML] The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA
EG Moss, RC Lee, V Ambros - Cell, 1997 - cell.com
Mutations in the heterochronic gene lin-28 of C. elegans cause precocious development
where diverse events specific to the second larval stage are skipped. lin-28 encodes a …
where diverse events specific to the second larval stage are skipped. lin-28 encodes a …
Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
K Seggerson, L Tang, EG Moss - Developmental biology, 2002 - Elsevier
The heterochronic gene lin-28 of the nematode Caenorhabditis elegans controls the relative
timing of diverse developmental events during the animal's larval stages. lin-28 is stage …
timing of diverse developmental events during the animal's larval stages. lin-28 is stage …
Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28.
Heterochronic genes form a regulatory pathway that controls the temporal sequence of the
Caenorhabditis elegans postembryonic cell lineage. One of these genes, lin-14, encodes a …
Caenorhabditis elegans postembryonic cell lineage. One of these genes, lin-14, encodes a …
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
RC Lee, RL Feinbaum, V Ambros - cell, 1993 - cell.com
Summary h-4 is essential for the normal temporal control of diverse postembryonic
developmental events in C. elegans./in-4 acts by negatively regulating the level of LIN-14 …
developmental events in C. elegans./in-4 acts by negatively regulating the level of LIN-14 …
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
B Wightman, I Ha, G Ruvkun - Cell, 1993 - Elsevier
During C. elegans development, the temporal pattern of many cell lineages is specified by
graded activity of the heterochronic gene Lin-14. Here we demonstrate that a temporal …
graded activity of the heterochronic gene Lin-14. Here we demonstrate that a temporal …
The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans
AE Rougvie, V Ambros - Development, 1995 - journals.biologists.com
ABSTRACT A hierarchy of heterochronic genes, lin-4, lin-14, lin-28 and lin-29, temporally
restricts terminal differentiation of Caenorhabditis elegans hypodermal seam cells to the …
restricts terminal differentiation of Caenorhabditis elegans hypodermal seam cells to the …
A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.
I Ha, B Wightman, G Ruvkun - Genes & development, 1996 - genesdev.cshlp.org
The Caenorhabditis elegans heterochronic gene lin-14 generates a temporal gradient of the
LIN-14 proteins to control stage-specific patterns of cell lineage during development. Down …
LIN-14 proteins to control stage-specific patterns of cell lineage during development. Down …
Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development.
B Wightman, TR Bürglin, J Gatto, P Arasu… - Genes & …, 1991 - genesdev.cshlp.org
The heterchronic gene lin-14 controls the temporal sequence of developmental events in the
Caenorhabditis elegans postembryonic cell lineage. It encodes a nuclear protein that …
Caenorhabditis elegans postembryonic cell lineage. It encodes a nuclear protein that …
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
The C. elegans heterochronic gene pathway consists of a cascade of regulatory genes that
are temporally controlled to specify the timing of developmental events. Mutations in …
are temporally controlled to specify the timing of developmental events. Mutations in …
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- small rnas lin 14
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- lin 4 posttranscriptional regulation