Transforming growth factor-beta 1 (TGF β-1) is an important mediator of liver-cell
proliferation and replication that is implicated in hepatic fibrosis (HF). Hepatic stellate cells …

BACKGROUND: Biliary atresia (BA) is an infantile disorder characterized by the obstruction
of a portion or the entirety of the extrahepatic bile ducts, leading to hepatic fibrosis and loss …

BACKGROUND/PURPOSE: Transforming growth factor-beta (TGF-β) 1 and 2 and their
receptors TβR-I, TβR-II, and TβR-III are powerful profibrogenic mediators in the body. Their …

Abstract Background and Aim: Biliary atresia (BA) is a serious liver disease in children.
Since transforming growth factor-β1 (TGF-β1) and epidermal growth factor (EGF) are …

Background: Biliary atresia (BA) is a neonatal cholangiopathy characterized by progressive
destruction of the biliary system resulting in liver cirrhosis. Residual bile drainage can …

Purpose: Biliary atresia (BA) is the most common indication of liver transplantation in
children. Pathogenesis of hepatic fibrosis, which is a prominent feature of BA, remains …

Purpose Long-term survivors of biliary atresia (BA) sometimes experience liver dysfunction.
We evaluated the prognostic factors for long-term native liver survival (NLS) in BA patients …

Purpose The objective of this study was to determine the predictive index for prognosis in
patients with biliary atresia (BA). Methods A total of 71 patients were divided into two groups …

Connective tissue growth factor (CTGF) is a newly described protein that stimulates
transforming growth factor-β1 (TGF-β1). We evaluated the expression of CTGF mRNA in …

Extrahepatic biliary atresia is a severe neonatal liver disease resulting from a sclerosing
cholangiopathy of unknown etiology. Although biliary obstruction may be surgically …