Progression of oral mucosal lesions is generally marked by changes in the concentration of
the intrinsic fluorophores such as collagen, nicotinamide adenine dinucleotide (NADH) …

Background Normal and cancerous tissues have distinct auto-fluorescence properties
because of differences in their biophysical and biochemical agents. Scientific evidences …

Optoelectronics techniques to induce protoporphyrin IX fluorescence with topically applied 5-
aminolevulinic acid on the oral mucosa have been developed to noninvasively detect oral …

BACKGROUND: Early detection of premalignant/malignant lesions in the oral cavity can
certainly improve the patient's prognosis. This study presents fluorescence imaging with the …

In vivo detection of oral precancer has been carried out by a fluorescence-based, in-house-
developed handheld probe on three groups: oral squamous cell carcinoma (OSCC) …

Objectives: Early cancer detection is the best way to improve the prognosis of patients with
oral cancer. Therefore this study presents quantitative fluorescence measurements and …

Fluorescence excitation spectroscopy (FES) is an emerging approach to cancer detection.
The goal of this pilot study is to evaluate the diagnostic potential of FES technique for the …

Abstract Background and Objectives Studies of 5‐aminolevulinic acid‐induced
protoporphyrin IX fluorescence have shown a sensitivity of 95–100% for oral cancer …

Abstract Studies of 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PPIX)
fluorescence have shown a sensitivity of 95-100% for oral cancer diagnosis, but the …

Oral cancer is a public health problem with relevant incidence in the world population. The
affected patient usually presents advanced stage disease and the consequence of this delay …