Folate administration substantially reduces the risk on neural tube defects (NTD). The
interest for studying a disturbed homocysteine (Hcy) metabolism in relation to NTD was …

Folate administration substantially reduces the risk on neural tube defects (NTD). The
interest for a disturbed homocysteine (Hcy) metabolism in relation to NTD was raised by the …

It is now well-established that folic acid, taken periconceptionally, can reduce the risk of
neural tube defects (NTDs). Recent work has demonstrated that an abnormality of …

In this paper, we trace the history of current research into the genetic and biochemical
mechanisms that underlie folate‐preventable neural tube defects (NTDs). The inspired …

The maternal vitamin status, especially of folate, is involved in the pathogenesis of neural-
tube defects (NTDs). Maternal folate administration can prevent these malformations. The …

Neural tube defects (NTD) are likely to result from an interaction of several genes and
environmental factors. Because periconceptional folate intake reduces the NTD risk in the …

Neural-tube defects (NTD) are common congenital malformations that can lead to severe
disability or even death. Periconceptional supplementation with the B-vitamin folic acid has …

Background Neural Tube Defects (NTDs) are among the most prevalent and most severe
congenital malformations worldwide. Polymorphisms in key genes involving the folate …

Effective supplementation with folate, which prevents neural tube defect (NTD) occurrence,
and high homocysteine levels in the blood of NTD children's mothers suggest that genes …

Objective: To investigate the contribution of polymorphic variation in genes involved in the
folate-dependent homocysteine pathway in the aetiology of neural tube defects (NTD) …