Folate, homocysteine and neural tube defects: an overview
NMJ Van Der Put, HWM Van Straaten… - Experimental …, 2001 - journals.sagepub.com
Folate administration substantially reduces the risk on neural tube defects (NTD). The
interest for studying a disturbed homocysteine (Hcy) metabolism in relation to NTD was …
interest for studying a disturbed homocysteine (Hcy) metabolism in relation to NTD was …
Neural tube defects and a disturbed folate dependent homocysteine metabolism
NMJ van der Put, HJ Blom - European Journal of Obstetrics & Gynecology …, 2000 - Elsevier
Folate administration substantially reduces the risk on neural tube defects (NTD). The
interest for a disturbed homocysteine (Hcy) metabolism in relation to NTD was raised by the …
interest for a disturbed homocysteine (Hcy) metabolism in relation to NTD was raised by the …
A genetic defect in 5, 10 methylenetetrahydrofolate reductase in neural tube defects
AS Whitehead, P Gallagher, JL Mills… - … Journal of Medicine, 1995 - academic.oup.com
It is now well-established that folic acid, taken periconceptionally, can reduce the risk of
neural tube defects (NTDs). Recent work has demonstrated that an abnormality of …
neural tube defects (NTDs). Recent work has demonstrated that an abnormality of …
The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects
In this paper, we trace the history of current research into the genetic and biochemical
mechanisms that underlie folate‐preventable neural tube defects (NTDs). The inspired …
mechanisms that underlie folate‐preventable neural tube defects (NTDs). The inspired …
Maternal hyperhomocysteinemia: a risk factor for neural-tube defects?
RPM Steegers-Theunissen, GHJ Boers, FJM Trijbels… - Metabolism, 1994 - Elsevier
The maternal vitamin status, especially of folate, is involved in the pathogenesis of neural-
tube defects (NTDs). Maternal folate administration can prevent these malformations. The …
tube defects (NTDs). Maternal folate administration can prevent these malformations. The …
Interaction of folate and homocysteine pathway genotypes evaluated in susceptibility to neural tube defects (NTD) in a German population
B Richter, K Stegmann, B Röper, I Böddeker… - Journal of human …, 2001 - nature.com
Neural tube defects (NTD) are likely to result from an interaction of several genes and
environmental factors. Because periconceptional folate intake reduces the NTD risk in the …
environmental factors. Because periconceptional folate intake reduces the NTD risk in the …
Genetic variation in genes of folate metabolism and neural-tube defect risk
Neural-tube defects (NTD) are common congenital malformations that can lead to severe
disability or even death. Periconceptional supplementation with the B-vitamin folic acid has …
disability or even death. Periconceptional supplementation with the B-vitamin folic acid has …
Genetic variants in the folate pathway and the risk of neural tube defects: a meta-analysis of the published literature
T Zhang, J Lou, R Zhong, J Wu, L Zou, Y Sun, X Lu… - PLos one, 2013 - journals.plos.org
Background Neural Tube Defects (NTDs) are among the most prevalent and most severe
congenital malformations worldwide. Polymorphisms in key genes involving the folate …
congenital malformations worldwide. Polymorphisms in key genes involving the folate …
[PDF][PDF] Genetic basis of neural tube defects. II. Genes correlated with folate and methionine metabolism
M Gos, A Szpecht-Potocka - Journal of applied genetics, 2002 - alkamallab.com
Effective supplementation with folate, which prevents neural tube defect (NTD) occurrence,
and high homocysteine levels in the blood of NTD children's mothers suggest that genes …
and high homocysteine levels in the blood of NTD children's mothers suggest that genes …
Gene–gene interaction in folate-related genes and risk of neural tube defects in a UK population
Objective: To investigate the contribution of polymorphic variation in genes involved in the
folate-dependent homocysteine pathway in the aetiology of neural tube defects (NTD) …
folate-dependent homocysteine pathway in the aetiology of neural tube defects (NTD) …
相关搜索
- neural tube defect risk
- neural tube folate metabolism
- homocysteine metabolism tube defects
- folate pathway tube defects
- folate metabolism defect risk
- methylenetetrahydrofolate reductase tube defects
- gene interaction tube defects
- german population tube defects
- neural tube genetic variation
- meta analysis tube defects
- homocysteine pathway tube defects
- methionine metabolism tube defects
- genetic variants tube defects
- genetic basis tube defects