Parkinson's disease (PD) is a common neurodegenerative disorder. Neuronal cell death in
PD is still poorly understood, despite a wealth of potential pathogenic mechanisms and …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder in the
world. Motor impairment seen in PD is associated with dopaminergic neurotoxicity in the …

Despite major advances in our understanding of the initiating factors that trigger many
neurodegenerative disorders, to date, no novel disease-modifying therapies have been …

Neurodegenerative disease is characterized by the progressive deterioration of neuronal
function caused by the degeneration of synapses, axons, and ultimately the death of nerve …

There are common mechanisms shared by genetically or pathologically distinct
neurodegenerative diseases, such as excitotoxicity, mitochondrial deficits and oxidative …

Molecular pathways of programmed cell death (PCD) are activated in various
neurodegenerative disorders including Parkinson's disease, amyotrophic lateral sclerosis …

Concepts of pathogenesis in Parkinson's disease (PD) have been based on attempts to
understand the mechanisms responsible for nigral dopaminergic cell death. Pathogenesis …

Tightly orchestrated programmed cell death (PCD) signalling events occur during normal
neuronal development in a spatially and temporally restricted manner to establish the neural …

Parkinson disease (PD) is a complex neurodegenerative disorder with both motor and
nonmotor symptoms owing to a spreading process of neuronal loss in the brain. At present …

Current therapies for Parkinson's disease significantly improve the quality of life for patients
suffering from this neurodegenerative disease, yet none of the current therapies has been …