Background: The XRCC1 protein facilitates various DNA repair pathways; single-nucleotide
polymorphisms (SNPs) in this gene are associated with a risk of gastrointestinal cancer …

Background: The DNA repair gene XRCC1Arg399Gln gene polymorphism has been found
to be implicated in the development of various cancers, including colorectal cancer (CRC) …

DNA repair plays a critical role in protecting the genome of the cell from the insults of cancer-
causing agents. Genetic polymorphisms in DNA repair genes may influence individual …

Background: Non-synonymous polymorphisms in XRCC1 hase been shown to reduce
effectiveness of DNA repair and be associated with risk of certain cancers. In this study we …

Background: Stomach cancer is one of leading causes of death worldwide. In Thailand, the
incidence and mortality of stomach cancer are in the top ten for cancers. Effects of DNA …

Aim: The distribution of DNA repair gene XRCC1 and XRCC3 genotypes was used to
assess the potential influence of genetic polymorphisms on risk of colorectal cancer, and …

Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. This
study aimed to investigate the interaction between the presence of a polymorphism of the …

Objective: X-ray cross-complementing group 1 (XRCC1) and 8 Oxo guanine DNA-
glycosylase 1 (OGG1) genes are implicated in the repair of single-stranded breaks (SSBRs) …

Background: Alarming increased incidence of gastrointestinal (GI) cancer in rural parts of
Maharashtra intended us to elucidate association of polymorphism in DNA repair genes with …

The aim of this study was to investigate the role of the XRCC1 Arg399Gln polymorphism in
the susceptibility of a Kashmiri population to colorectal cancer (CRC). We investigated the …