Exploring multifunctional antioxidants as potential agents for management of neurological disorders
Free radical or oxidative stress may be a fundamental mechanism underlying several
human neurologic diseases. Therapy using free radical scavengers (antioxidants) has the …
human neurologic diseases. Therapy using free radical scavengers (antioxidants) has the …
Antioxidant therapeutic strategies in neurodegenerative diseases
C Morén, RM deSouza, DM Giraldo, C Uff - International journal of …, 2022 - mdpi.com
The distinguishing pathogenic features of neurodegenerative diseases include
mitochondrial dysfunction and derived reactive oxygen species generation. The neural …
mitochondrial dysfunction and derived reactive oxygen species generation. The neural …
Neurodegeneration by oxidative stress: a review on prospective use of small molecules for neuroprotection
E Singh, G Devasahayam - Molecular Biology Reports, 2020 - Springer
The intricate physiology of many Central Nervous System (CNS) disorders points towards
oxidative damages of neurons. Various studies have established that oxidative stress is a …
oxidative damages of neurons. Various studies have established that oxidative stress is a …
Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options
Free radicals are common outcome of normal aerobic cellular metabolism. In-built
antioxidant system of body plays its decisive role in prevention of any loss due to free …
antioxidant system of body plays its decisive role in prevention of any loss due to free …
Role of natural antioxidants on neuroprotection and neuroinflammation
D Nuzzo - Antioxidants, 2021 - mdpi.com
All cells continuously generate reactive oxygen species (ROS) through the respiratory chain
during the energy metabolism process. When ROS are maintained at low or moderate …
during the energy metabolism process. When ROS are maintained at low or moderate …
Neuroprotective effects of antioxidants in the management of neurodegenerative disorders: A literature review
Y Panahi, SM Rajaee, TP Johnston… - Journal of cellular …, 2019 - Wiley Online Library
It is proven that oxidative stress has a pivotal role in the process of neurodegeneration. The
use of antioxidants is an attractive method to prevent the incidence of neurodegenerative …
use of antioxidants is an attractive method to prevent the incidence of neurodegenerative …
Antioxidant strategies in protection against neurodegenerative disorders
The most common neurodegenerative diseases include Alzheimer's disease, Parkinson's
disease and stroke; they are devastating clinical problems which lack effective treatments …
disease and stroke; they are devastating clinical problems which lack effective treatments …
Antioxidant for neurological diseases and neurotrauma and bioengineering approaches
Antioxidants are a class of molecules with an innate affinity to neutralize reactive oxygen
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …
The discovery and development of new potential antioxidant agents for the treatment of neurodegenerative diseases
Introduction: Several neurodegenerative disorders (NDs) including Alzheimer's and
Huntington's diseases have had associations with the oxidative process and free radical …
Huntington's diseases have had associations with the oxidative process and free radical …
Neuroprotective effect of antioxidants in the brain
KH Lee, M Cha, BH Lee - International journal of molecular sciences, 2020 - mdpi.com
The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …