Oxidative stress and neurodegenerative disease.

LY Al-Ayadhi - Neurosciences Journal, 2004 - nsj.org.sa
Several disease conditions are believed to be related to oxygen free radical formation
including a number of neurodegenerative disorders. Therapy using free radical scavengers …

Natural antioxidants protect neurons in Alzheimer's disease and Parkinson's disease

B Zhao - Neurochemical Research, 2009 - Springer
Abstract “Modern” medicine and pharmacology require an effective medical drug with a
single compound for a specific disease. This seams very scientific but usually has …

Antioxidant therapies for neuroprotection—A review

RI Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2019 - mdpi.com
Although moderate concentrations of reactive oxygen species (ROS) and reactive nitrogen
species (RNS) are crucial for various physiological processes within the human body, their …

Delineation of neuroprotective effects and possible benefits of antioxidantstherapy for the treatment of Alzheimer's diseases by targeting mitochondrial-derived …

V Walia, D Kaushik, V Mittal, K Kumar, R Verma… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is considered the sixth leading cause of death in elderly patients
and is characterized by progressive neuronal degeneration and impairment in memory …

Multiple antioxidants in the prevention and treatment of neurodegenerative disease: analysis of biologic rationale

KN Prasad, WC Cole, AR Hovland… - Current opinion in …, 1999 - journals.lww.com
Parkinson's disease and Alzheimer's disease are major progressive neurologic disorders,
the risk of which increases with advancing age (65 years and over). In familial cases …

Oxidative stress, antioxidants and neurodegenerative diseases

I Casetta, V Govoni, E Granieri - Current pharmaceutical design, 2005 - ingentaconnect.com
It is widely accepted that oxidative stress increases with age, and that age is a major risk
factor for several neurodegenerative diseases such as Parkinson's disease and Alzheimer's …

[PDF][PDF] Significance of antioxidants in the treatment and prevention of neurodegenerative diseases

AO Fadaka, BO Ajiboye, I Adewale… - J …, 2019 - phytopharmajournal.com
Neurodegenerative diseases are ailments that disturb the brain, precisely the neurons. The
utmost mutual indicators include failures in stability, inhalation, movement, reflexes, motor …

Abrogating oxidative stress as a therapeutic strategy against Parkinson's disease: a mini review of the recent advances on natural therapeutic antioxidant and …

T Theofanous, M Kourti - Medicinal Chemistry, 2022 - ingentaconnect.com
Background: Reactive oxygen species (ROS) play a vital role in cell signaling when
maintained at low concentrations. However, when ROS production exceeds the neutralizing …

Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier

Y Gilgun-Sherki, E Melamed, D Offen - Neuropharmacology, 2001 - Elsevier
Oxidative stress (OS) has been implicated in the pathophysiology of many neurological,
particularly neurodegenerative diseases. OS can cause cellular damage and subsequent …

Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer's disease

DY Choi, YJ Lee, JT Hong, HJ Lee - Brain research bulletin, 2012 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease and most
common cause of dementia. However, there is no known way to halt or cure the …