Environmental DNA Methylation Signatures of Adolescent Victimization: Analysis of a Longitudinal Monozygotic Twin Sample, 2015-2020

CCY Wong - reshare.ukdataservice.ac.uk
Accumulating evidence suggests that individuals exposed to victimization at key
developmental stages may have different epigenetic fingerprints compared to those …

DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample

R Kandaswamy, E Hannon, L Arseneault, G Mansell… - Epigenetics, 2021 - Taylor & Francis
Accumulating evidence suggests that individuals exposed to victimization at key
developmental stages may have different epigenetic fingerprints compared to those …

Epigenetic impact of a 1-week intensive multimodal group program for adolescents with multiple adverse childhood experiences

P Kaliman, M Cosín-Tomás, A Madrid… - Scientific Reports, 2022 - nature.com
Adverse childhood experiences (ACEs, ie, abuse, neglect, household dysfunction) represent
a potential risk factor for a wide range of long-lasting diseases and shorter life expectancy …

-Beyond the limited evidence for an association between childhood maltreatment and DNA methylation: the moderating role of genetic sensitivity to the environment

M Comtois-Cabana, E Barr, A Coope… - …, 2024 - Elsevier
Background Existing evidence points to an inconsistent association between maltreatment
experiences and DNA methylation (DNAm) profiles. Yet, recent studies suggest that this …

Epigenetic signatures of childhood abuse and neglect: Implications for psychiatric vulnerability

CAM Cecil, RG Smith, E Walton, J Mill… - Journal of psychiatric …, 2016 - Elsevier
Childhood maltreatment is a key risk factor for poor mental and physical health. Recently,
variation in epigenetic processes, such as DNA methylation, has emerged as a potential …

Epigenetics of early-life adversity in youth: cross-sectional and longitudinal associations

JA Sumner, S Gambazza, X Gao, AA Baccarelli… - Clinical …, 2022 - Springer
Abstract Background Altered DNA methylation (DNAm) may be one pathway through which
early-life adversity (ELA) contributes to adverse mental and physical health outcomes. This …

A prospective study of time-dependent childhood adversity and DNA methylation across childhood and adolescence

AA Lussier, Y Zhu, BJ Smith, J Cerutti, AJ Simpkin… - medRxiv, 2021 - medrxiv.org
Background Children exposed to adversity often have epigenetic profiles, including DNA
methylation (DNAm) signatures, that differ from children without adversity histories. These …

Childhood abuse is associated with methylation of multiple loci in adult DNA

M Suderman, N Borghol, JJ Pappas… - BMC medical …, 2014 - Springer
Background Childhood abuse is associated with increased adult disease risk, suggesting
that processes acting over the long-term, such as epigenetic regulation of gene activity, may …

Analysis of DNA methylation in young people: limited evidence for an association between victimization stress and epigenetic variation in blood

SJ Marzi, K Sugden, L Arseneault… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: DNA methylation has been proposed as an epigenetic mechanism by which early-
life experiences become “embedded” in the genome and alter transcriptional processes to …

Childhood trauma and epigenetics: state of the science and future

N Gladish, SM Merrill, MS Kobor - Current Environmental Health Reports, 2022 - Springer
Abstract Purpose of Review There is a great deal of interest regarding the biological
embedding of childhood trauma and social exposures through epigenetic mechanisms …