Gold nanoparticles induce nanostructural reorganization of VEGFR2 to repress angiogenesis
Y Pan, H Ding, L Qin, X Zhao, J Cai… - Journal of biomedical …, 2013 - ingentaconnect.com
The inhibition of the binding between VEGFs and their receptors reduces angiogenesis and
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …
retards tumor growth. Owing to the large amount of antibodies required, the antibody-based …
Inhibition effects of gold nanoparticles on proliferation and migration in hepatic carcinoma-conditioned HUVECs
Y Pan, Q Wu, R Liu, M Shao, J Pi, X Zhao… - Bioorganic & medicinal …, 2014 - Elsevier
Tumor angiogenesis is a complicated process based upon a sequence of interactions
between tumor and vessel endothelial cells. Tumor conditioned medium has been widely …
between tumor and vessel endothelial cells. Tumor conditioned medium has been widely …
Gold nanoparticles induce tumor vessel normalization and impair metastasis by inhibiting endothelial Smad2/3 signaling
N Huang, Y Liu, Y Fang, S Zheng, J Wu, M Wang… - ACS …, 2020 - ACS Publications
Gold nanoparticles (AuNPs) are a promising nanomaterial due to their drug-delivery
properties and inherent anti-neoplastic activity. Here, we focused on the anti-neoplastic …
properties and inherent anti-neoplastic activity. Here, we focused on the anti-neoplastic …
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial–mesenchymal transition inhibition
Angiogenesis is a process by which vessels are formed through preexisting ones, and this
plays a key role in the progression of solid tumors. However, tumor vessels are influenced …
plays a key role in the progression of solid tumors. However, tumor vessels are influenced …
Cellular localization and biological effects of 20nm‐gold nanoparticles
G Tan, MA Onur - … of Biomedical Materials Research Part A, 2018 - Wiley Online Library
Gold nanoparticles (AuNPs) have recently emerged as prominent vehicles for many
biomedical applications from sensing to delivery. The relevant literature contains conflicting …
biomedical applications from sensing to delivery. The relevant literature contains conflicting …
Gold Nanoparticles Inhibit VEGF165‐Induced Migration and Tube Formation of Endothelial Cells via the Akt Pathway
Y Pan, Q Wu, L Qin, J Cai, B Du - BioMed research international, 2014 - Wiley Online Library
The early stages of angiogenesis can be divided into three steps: endothelial cell
proliferation, migration, and tube formation. Vascular endothelial growth factor (VEGF) is …
proliferation, migration, and tube formation. Vascular endothelial growth factor (VEGF) is …
Synthesis and antitumor application of antiangiogenetic gold nanoclusters
Q Li, R Zhou, Y Sun, D Xiao, M Liu… - … Applied Materials & …, 2021 - ACS Publications
Conventional antiangiogenetic inhibitors suffered from poor delivery problems that result in
unsatisfactory antitumor treatment efficacy. Although the liposomes or nanomaterial-based …
unsatisfactory antitumor treatment efficacy. Although the liposomes or nanomaterial-based …
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2
W Huang, Y Xing, L Zhu, J Zhuo, M Cai - Experimental Cell Research, 2021 - Elsevier
Sorafenib is a multi-kinase inhibitor that has been highlighted as a tumor suppressor due to
its anti-proliferative and anti-angiogenic properties, whereas the clinical application of …
its anti-proliferative and anti-angiogenic properties, whereas the clinical application of …
Gold Nanoparticles Disrupt Tumor Microenvironment - Endothelial Cell Cross Talk To Inhibit Angiogenic Phenotypes in Vitro
Y Zhang, X Xiong, Y Huai, A Dey… - Bioconjugate …, 2019 - ACS Publications
It is currently recognized that perpetual cross talk among key players in tumor
microenvironment such as cancer cells (CCs), cancer associated fibroblasts (CAFs), and …
microenvironment such as cancer cells (CCs), cancer associated fibroblasts (CAFs), and …
Mechanism of anti-angiogenic property of gold nanoparticles: role of nanoparticle size and surface charge
Discovering therapeutic inorganic nanoparticles (NPs) is evolving as an important area of
research in the emerging field of nanomedicine. Recently, we reported the anti-angiogenic …
research in the emerging field of nanomedicine. Recently, we reported the anti-angiogenic …
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