The ERK, p38MAPK, JNK mitogen-activated protein kinases (MAPKs) are intracellular
signaling pathways that play a pivotal role in many essential cellular processes such as …

Mitogen-activated protein (MAP) kinases are a family of serine/threonine kinases that play a
central role in transducing extracellular cues into a variety of intracellular responses ranging …

Mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs including
embryogenesis, proliferation, differentiation and apoptosis based on cues derived from the …

Both mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 function
downstream of the proto-oncogene product Raf in signaling pathways that affect cell …

Mammalian cells contain at least three signaling systems which are structurally related to the
mitogen-activated protein kinase (MAPK) pathway. Growth factors acting through Ras …

Mitogen-activated protein kinases (MAPKs) are components of sequential kinase cascades
that are activated in response to a variety of extracellular signals. Members of the MAPK …

The p38 MAPK (mitogen-activated protein kinase) signalling pathway allows cells to
interpret a wide range of external signals and respond appropriately by generating a …

MAP kinase (MAPK) cascades are composed of a MAPK, MAPK kinase (MAPKK), and a
MAPKK kinase (MAPKKK). Despite the existence of numerous components and ample …

The intracellular signalling field is dominated by the mitogen-activated protein kinase
(MAPK) cascade and its control, which involves the small GTPase Ras and sequential …

Evolutionarily conserved from yeast to man, mitogen-activated protein kinase (MAPK)
pathways respond to a variety of disparate signals which induce differentiation, proliferation …