Verapamil and digoxin are often used in combination and clinical experience suggests that
verapamil may increase digoxin toxicity. We have explored the effects of verapamil upon …

Verapamil and digoxin are frequently used in combination, and clinical experience suggests
that verapamil may increase digoxin toxicity. We have investigated the influence of …

Recent studies have shown a significant increase in plasma digoxin concentration during
verapamil treatment. This phenomenon has been attributed in part to reduced renal …

To explore a possible interaction between digoxin and verapamil, a single‐dose kinetic
study of digoxin was performed and then repeated after 10 days of verapamil treatment in …

Atropine alone in the two lower doses (20mg/kg and 40mg/kg) did not produce any
arrhythmias while 80mg/kg of atropine produced arrhythmias in 33% of animals after 31.0+ …

Digoxin and Verapamil may often be used in association in heart diseases; we tested
whether this coadministration increases digitalis activity. Ten patients with failing heart were …

There is a pharmacokinetic interaction between digoxin and diazepam that increases the
elimination half-life of digoxin. It may be due to a reduction of digoxin tissue concentrations …

Conflicting conclusions have been reported about interaction of calcium channel blockers
with digoxin. The effects of verapamil (240 mg/day) and a new dihydropyridine calcium …

Digoxin was infused intravenously 27.5 μg/min. to guinea pigs. By means of the ECG doses
of digoxin needed to cause ventricular extrasystoles (VES), ventricular fibrillation (VF), and …

The interaction between digoxin and verapamil was studied in six patients (mean age±SD,
61±5 years) with chronic atrial fibrillation. The effects of adding verapamil (240 mg/day) on …