One decade of glioblastoma multiforme surgery in 342 elderly patients: what have we learned?

DH Heiland, G Haaker, R Watzlawick, D Delev… - Journal of Neuro …, 2018 - Springer
Introduction Glioblastoma multiforme (GBM) is the most common malignant primary brain
tumor in adults with peak incidence in patients older than 65 years. These patients are …

Treatment results and outcome in elderly patients with glioblastoma multiforme–a retrospective single institution analysis

M Hoffermann, L Bruckmann, KM Ali, M Asslaber… - Clinical Neurology and …, 2015 - Elsevier
Objective Although glioblastoma multiforme is more common in patients older than 65 years,
the elderly population is often excluded from clinical studies. Decision making in this …

Outcomes and patterns of care in elderly patients with glioblastoma multiforme

RS Nunna, SI Khalid, S Patel, A Sethi, M Behbahani… - World neurosurgery, 2021 - Elsevier
Background Glioblastoma multiforme (GBM) is the most common primary malignant brain
tumor in adults, with an increased incidence among the elderly. However, the optimal …

Glioblastoma multiforme in the elderly: a therapeutic challenge

A Mangiola, G Maira, P De Bonis, M Porso… - Journal of neuro …, 2006 - Springer
Introduction: Elderly patients with glioblastoma multiforme (GBM) are frequently excluded
from cancer therapy trials, treated suboptimally or not treated at all. The average survival in …

Is surgical resection useful in elderly newly diagnosed glioblastoma patients? Outcome evaluation and prognostic factors assessment

F Pessina, P Navarria, L Cozzi, R Rudà, MC Nibali… - Acta …, 2018 - Springer
Background The incidence of glioblastoma among elderly patients is constantly increasing.
The value of radiation therapy and concurrent/adjuvant chemotherapy has been widely …

Glioblastoma multiforme of the elderly: the prognostic effect of resection on survival

C Ewelt, M Goeppert, M Rapp, HJ Steiger… - Journal of neuro …, 2011 - Springer
According to recent developments the best treatment options for glioblastoma (GBM) consist
in maximum safe resection and additional adjuvant treatment with radiotherapy (RT) and …

To resect or not to resect? Risks and benefits of surgery in older patients with glioblastoma

Y Ahmadipour, L Rauschenbach, O Gembruch… - Journal of Geriatric …, 2020 - Elsevier
Introduction Glioblastoma multiforme (GBM) has a peak incidence in patients older than 65
years. The aim of the present study is to evaluate the impact of surgical strategy on short-and …

Glioblastoma in the elderly: the effect of aggressive and modern therapies on survival

R Babu, JM Komisarow, VJ Agarwal… - Journal of …, 2016 - thejns.org
OBJECT The prognosis of elderly patients with glioblastoma (GBM) is universally poor.
Currently, few studies have examined postoperative outcomes and the effects of various …

Surgical strategies for older patients with glioblastoma

T Barak, S Vetsa, A Nadar, L Jin, TP Gupte… - Journal of Neuro …, 2021 - Springer
Objective While adjuvant treatment regimens have been modified for older patients with
glioblastoma (GBM), surgical strategies have not been tailored. Methods Clinical data of 48 …

Is age an additional factor in the treatment of elderly patients with glioblastoma? A new stratification model: an Italian Multicenter Study

T Ius, T Somma, R Altieri, FF Angileri… - Neurosurgical …, 2020 - thejns.org
OBJECTIVE Approximately half of glioblastoma (GBM) cases develop in geriatric patients,
and this trend is destined to increase with the aging of the population. The optimal strategy …