Optical coherence elastography for assessing the influence of intraocular pressure on elastic wave dispersion in the cornea

MG Sun, T Son, J Crutison, V Guaiquil, S Lin… - Journal of the …, 2022 - Elsevier
The cornea is a highly specialized organ that relies on its mechanical stiffness to maintain its
aspheric geometry and refractive power, and corneal diseases such as keratoconus have …

In vivo Optical Coherence Elastography Unveils Spatial Variation of Human Corneal Stiffness

GY Li, X Feng, SH Yun - IEEE Transactions on Biomedical …, 2023 - ieeexplore.ieee.org
Objective: The mechanical properties of corneal tissues play a crucial role in determining
corneal shape and have significant implications in vision care. This study aimed to address …

Quantitative assessment of corneal viscoelasticity using optical coherence elastography and a modified Rayleigh–Lamb equation

Z Han, SR Aglyamov, J Li, M Singh… - … of biomedical optics, 2015 - spiedigitallibrary.org
We demonstrate the use of a modified Rayleigh–Lamb frequency equation in conjunction
with noncontact optical coherence elastography to quantify the viscoelastic properties of the …

Simultaneous tensile and shear measurement of the human cornea in vivo using S0-and A0-wave optical coherence elastography

GY Li, X Feng, SH Yun - Acta Biomaterialia, 2024 - Elsevier
Understanding corneal stiffness is valuable for improving refractive surgery, detecting
corneal abnormalities, and assessing intraocular pressure. However, accurately measuring …

[HTML][HTML] In vivo human corneal shear-wave optical coherence elastography

G Lan, SR Aglyamov, KV Larin… - Optometry and Vision …, 2021 - journals.lww.com
PURPOSE Determining corneal biomechanical properties is a long-standing challenge.
Elasticity imaging methods have recently been developed and applied for clinical evaluation …

Measuring mechanical wave speed, dispersion, and viscoelastic modulus of the cornea using optical coherence elastography

A Ramier, B Tavakol, SH Yun - Optics express, 2019 - opg.optica.org
Acoustic wave velocity measurement based on optical coherence tomography (OCT) is a
promising approach to assess the mechanical properties of biological tissues and soft …

In vivo measurement of shear modulus of the human cornea using optical coherence elastography

A Ramier, AM Eltony, YT Chen, F Clouser… - Scientific reports, 2020 - nature.com
Corneal stiffness plays a critical role in shaping the cornea with respect to intraocular
pressure and physical interventions. However, it remains difficult to measure the mechanical …

Assessment of corneal viscoelasticity using elastic wave optical coherence elastography

Z Jin, Y Zhou, M Shen, Y Wang, F Lu… - Journal of …, 2020 - Wiley Online Library
The corneal viscoelasticity have great clinical significance, such as the early diagnosis of
keratoconus. In this work, an analysis method which utilized the elastic wave velocity …

[HTML][HTML] Noncontact acoustic micro-tapping optical coherence elastography for quantification of corneal anisotropic elasticity: in vivo rabbit study

MA Kirby, G Regnault, I Pelivanov… - … Vision Science & …, 2023 - iovs.arvojournals.org
Purpose: The purpose of this study was to demonstrate accurate measurement of corneal
elastic moduli in vivo with noncontact and noninvasive optical coherence elastography …

[HTML][HTML] Delineating corneal Elastic anisotropy in a porcine model using noncontact OCT elastography and ex vivo mechanical tests

MA Kirby, JJ Pitre Jr, HC Liou, DS Li, RK Wang… - Ophthalmology …, 2021 - Elsevier
Purpose To compare noncontact acoustic microtapping (AμT) OCT elastography (OCE) with
destructive mechanical tests to confirm corneal elastic anisotropy. Design Ex vivo laboratory …