Cannabis is among the most widely consumed psychoactive drugs around the world and
cannabis use disorder (CUD) has no current approved pharmacological treatment. Nicotine …

Cessation from prolonged use of∆ 9‐tetrahydrocannabinol (THC), the primary active
compound responsible for the cannabimimetic effects of cannabis, results in a mild to …

Rationale Several lines of evidence suggest that endocannabinoid and nicotinic cholinergic
systems are implicated in the regulation of different physiological processes, including …

A growing body of evidence suggests that the endogenous cannabinoid system modulates
the addictive properties of nicotine, the main component of tobacco that produces rewarding …

Nicotine is a highly addictive drug found in tobacco that drives its continued use despite the
harmful consequences. The initiation of nicotine abuse involves the mesolimbic dopamine …

Nicotine, the main psychoactive component in tobacco smoke, appears to play a major role
in tobacco addiction, producing a high morbidity and mortality in the world. A great amount …

Tobacco addiction is one of the leading preventable causes of mortality in the world and
nicotine appears to be the main critical psychoactive component in establishing and …

Nicotine addiction is a complex behavioural alteration, in which many neuronal pathways
and neurotransmitters are involved. For a long time, dopamine has been considered one of …

Tobacco use is one of the leading preventable causes of death in developed countries.
Since existing medications are only partially effective in treating tobacco smokers, there is a …

Multiple studies suggest a pivotal role of the endocannabinoid system in the regulation of
the reinforcing effects of various substances of abuse. Different approaches have been used …