MicroRNAs in colorectal cancer: translation of molecular biology into clinical application

O Slaby, M Svoboda, J Michalek, R Vyzula - Molecular cancer, 2009 - Springer
MicroRNAs (miRNAs) are small non-coding RNAs 18-25 nucleotides in length that
downregulate gene expression during various crucial cell processes such as apoptosis …

MicroRNAs in colorectal cancer: small molecules with big functions

Y Xuan, H Yang, L Zhao, WB Lau, B Lau, N Ren, Y Hu… - Cancer letters, 2015 - Elsevier
Colorectal cancer (CRC) is the third most lethal malignancy, with pathogenesis intricately
dependent upon microRNAs (miRNAs). miRNAs are short, non-protein coding RNAs …

[HTML][HTML] MicroRNAs potential utility in colon cancer: Early detection, prognosis, and chemosensitivity

M Hollis, K Nair, A Vyas, LS Chaturvedi… - World journal of …, 2015 - ncbi.nlm.nih.gov
Over the past decade, research has shown that aberrant expression of microRNA (miRNA)
is involved in colorectal cancer development and progression. MicroRNAs are small …

The dual role of microRNAs in colorectal cancer progression

L Ding, Z Lan, X Xiong, H Ao, Y Feng, H Gu… - International journal of …, 2018 - mdpi.com
Colorectal cancer (CRC) is responsible for one of the major cancer incidence and mortality
worldwide. It is well known that MicroRNAs (miRNAs) play vital roles in maintaining the cell …

[HTML][HTML] MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer

V Stiegelbauer, S Perakis, A Deutsch… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer in western countries. Despite
significant improvement in available treatment options, CRC still remains the second leading …

[HTML][HTML] MicroRNAs as biomarkers in colorectal cancer

K Schee, Ø Fodstad, K Flatmark - The American journal of pathology, 2010 - Elsevier
Colorectal cancer is a leading cause of cancer-related morbidity and mortality in the Western
world. While improved diagnostic surveillance and treatment strategies involving surgery …

[HTML][HTML] MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer

L Cekaite, PW Eide, GE Lind, RI Skotheim, RA Lothe - Oncotarget, 2016 - ncbi.nlm.nih.gov
Gene expression is in part regulated by microRNAs (miRNAs). This review summarizes the
current knowledge of miRNAs in colorectal cancer (CRC); their role as growth regulators, the …

The impact of microRNAs on colorectal cancer

C Faber, T Kirchner, F Hlubek - Virchows Archiv, 2009 - Springer
MicroRNAs are small RNAs that regulate gene expression at the post-transcriptional level.
After their discovery 15 years ago, a new layer of gene regulation was introduced into every …

MicroRNAs: Potential candidates for diagnosis and treatment of colorectal cancer

A Moridikia, H Mirzaei, A Sahebkar… - Journal of cellular …, 2018 - Wiley Online Library
Colorectal cancer (CRC) is known as the third common cancer worldwide and an important
public health problem in different populations. Several genetics and environmental risk …

MicroRNA in colorectal cancer: from benchtop to bedside

WKK Wu, PTY Law, CW Lee, CH Cho, D Fan… - …, 2011 - academic.oup.com
Colon carcinogenesis represents a stepwise progression from benign polyps to invasive
adenocarcinomas and distant metastasis. It is believed that these pathologic changes are …