Oxidative stress and liver injury are strongly associated. Oxidative stress in the liver can be
triggered during different conditions and by specific etiologies, including hepatotoxins …

The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

This chapter describes the implication of oxidative stress in the progression of the liver
diseases with higher prevalence worldwide: nonalcoholic fatty liver disease, cholestasis …

The liver plays a central role in the biotransformation of a variety of drugs and xenobiotics.
During the biotransformation of drugs and chemicals, the liver generates various reactive …

The inflammatory response is of prime importance in liver disease, irrespective of inciting
cause, and is inextricably linked to oxidative stress and the generation of reactive oxygen …

The role of oxidative stress in causing liver diseases emerged in the early 1960s from the
laboratories of Trevor Slater, Mario Umberto Dianzani and others. These pioneering works …

In humans, oxidative stress and antioxidant defenses are the sum of a complicated network
of enzymatic and non‐enzymatic processes. Depending on the stage and severity of …

Liver damage ranges from acute hepatitis to hepatocellular carcinoma, through apoptosis,
necrosis, inflammation, immune response, fibrosis, ischemia, altered gene expression and …

Oxidative stress is importantly involved in the pathophysiology of various liver diseases. The
redox state participates on the course of the inflammatory, metabolic and proliferative liver …