The important role of dopamine (DA) in mediating feeding behavior and the positive
reinforcing effects of some drugs is well recognized. Less widely studied is how feeding …

The high co-morbidity of eating disorders and substance abuse suggests that nutritional
status can impact vulnerability to drug abuse. These studies used rats to examine the effects …

Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …

The aim of the present study was to determine the behavioural effects of the selective
dopamine D1 receptor agonist, SKF 38393, and of the selective dopamine D2/D3 receptor …

Stimulation or blockade of various dopamine receptor subtypes is associated with reduced
feeding. For example, D2 receptor agonists suppress feeding in food‐deprived and free …

Across species, the brain evolved to respond to natural rewards such as food and sex.
These physiological responses are important for survival, reproduction and evolutionary …

Obesity can derive from a variety of causes (ie, genes, culture, nutrition intake, physical
activity). 1 Although maintenance of an appropriate body weight requires balance between …

Over the last few years, the concept of food addiction has become a common feature in the
scientific literature, as well as the popular press. Nevertheless, the use of the term addiction …

BRAIN DOPAMINE HAS BEEN LINKED to reward function by its importance first for the habit-
forming actions of addictive drugs, then for direct electrical stimulation of the brain, and …

In 2010, Johnson and Kenny provided conclusive evidence that extended access to a
Western-style diet promotes addictive-like behavior in rats by downregulating D2 receptors …