Identification of male germ cells undergoing apoptosis in adult rats
MH Brinkworth, GF Weinbauer, S Schlatt… - …, 1995 - rep.bioscientifica.com
The possible role of apoptosis in spontaneous or induced germ cell death was investigated
by treating adult male rats with either a GnRH antagonist (112.5 μg kg− 1 day− 1 for 14 …
by treating adult male rats with either a GnRH antagonist (112.5 μg kg− 1 day− 1 for 14 …
Induction of apoptotic cell death in the seminiferous tubule of the adult rat testis: assessment of the germ cell types that exhibit the ability to enter apoptosis after …
J Blanco‐Rodríguez… - International journal of …, 1996 - Wiley Online Library
The involvement of apoptosis in germ cell degeneration in the adult rat testis after
gonadotrophin suppression has recently been shown in several studies, which have …
gonadotrophin suppression has recently been shown in several studies, which have …
Apoptosis in testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages
H Billig, I Furuta, C Rivier, J Tapanainen… - …, 1995 - academic.oup.com
Recent studies have demonstrated apoptotic DNA fragmentation in the testis of immature
rats deprived of gonadotropins. However, the exact cell type undergoing apoptosis during …
rats deprived of gonadotropins. However, the exact cell type undergoing apoptosis during …
Involvement of apoptosis in the induction of germ cell degeneration in adult rats after gonadotropin-releasing hormone antagonist treatment
AP Hikim, C Wang, A Leung, RS Swerdloff - Endocrinology, 1995 - academic.oup.com
In adult mammals, including man, germ cell death is conspicuous during spermatogenesis
and plays a pivotal role in sperm output. The possible mechanism (s) underlying this …
and plays a pivotal role in sperm output. The possible mechanism (s) underlying this …
Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation
AP Sinha Hikim, TB Rajavashisth, IS Hikim… - Biology of …, 1997 - academic.oup.com
The major objectives of the present study were to document the temporal and stage-specific
acceleration of germ cell apoptosis in adult rats after selective suppression of pituitary …
acceleration of germ cell apoptosis in adult rats after selective suppression of pituitary …
Spontaneous germ cell death in the testis of the adult rat takes the form of apoptosis: re‐evaluation of cell types that exhibit the ability to die during spermatogenesis
J Blanco‐Rodríguez, C Martínez‐García - Cell proliferation, 1996 - Wiley Online Library
Spontaneous germ cell degeneration occurs in the testis of the adult rat. Accumulating data
supports the idea that this degeneration takes place via apoptosis. We have determined that …
supports the idea that this degeneration takes place via apoptosis. We have determined that …
Apoptosis and spermatogenesis: evidence from an in vivo model of testosterone withdrawal in the adult rat
L Troiano, MF Fustini, E Lovato, A Frasoldati… - Biochemical and …, 1994 - Elsevier
The seminiferous epithelium is a highly proliferating tissue in which germ cell" degeneration"
is a constant feature. Recent data based on morphological analysis have shown that …
is a constant feature. Recent data based on morphological analysis have shown that …
Quantification of apoptotic testicular germ cells in normal and methoxyacetic acid‐treated mice as determined by flow cytometry
H KRISHNAMURTHY, GE WEINBAUER… - Journal of …, 1998 - Wiley Online Library
Several studies have reported the occurrence and significance of programmed ceil death
(apoptosis) of testicular germ cells in mammals. In those studies, apoptotic germ cells were …
(apoptosis) of testicular germ cells in mammals. In those studies, apoptotic germ cells were …
Insights into male germ cell apoptosis due to depletion of gonadotropins caused by GnRH antagonists
The role of pituitary gonadotropins in the regulation of spermatogenesis has been
unequivocally demonstrated, although, the precise mechanism of this regulation is not …
unequivocally demonstrated, although, the precise mechanism of this regulation is not …
Apoptosis precedes detachment of germ cells from the seminiferous epithelium after hormone suppression by short-term oestradiol treatment of rats.
J Blanco-Rodriguez… - International journal of …, 1998 - europepmc.org
Spermatogenesis is a highly synchronized process in which FSH and testosterone are
considered the major regulators. Nevertheless, the mechanism by which these hormones …
considered the major regulators. Nevertheless, the mechanism by which these hormones …