TNF‐α, TNF‐β and IL‐4 gene polymorphisms in Iranian patients with multiple sclerosis

E Kamali‐Sarvestani, A Nikseresht… - Acta neurologica …, 2007 - Wiley Online Library
Objective–To investigate the association between tumor necrosis factor‐α (TNF‐α) G‐308A,
tumor necrosis factor‐β (TNF‐β) G+ 252A and interleukin‐4 (IL‐4) C‐590T polymorphisms …

IL-1, IL-1R and TNFalpha gene polymorphisms in Iranian patients with multiple sclerosis

SH SARIAL, MA Shokrgozar, AA Amirzargar, F Shokri… - 2008 - sid.ir
Different research groups have extensively studied the associations of cytokine GENE
POLYMORPHISM s in different diseases. The role of CYTOKINES GENE POLYMORPHISM …

TNF‐α promoter polymorphisms in multiple sclerosis: no association with− 308 and− 238 alleles, but the− 857 alleles in associated with the disease in Turkish patients

A Akcali, S Pehlivan, M Pehlivan… - International journal …, 2010 - Wiley Online Library
Dysregulation in the expression of pro‐and anti‐inflammatory cytokines is one of the
milestones in multiple sclerosis (MS) development and progression. Tumour necrosis factor …

Cytokines genes polymorphisms and risk of multiple sclerosis

M Izad, M Vodjgani, MH Niknam, A Amirzargar… - The American journal of …, 2010 - Elsevier
Association studies of proinflammatory and anti-inflammatory cytokines single nucleotide
polymorphisms with multiple sclerosis (MS) in population with different ethnic background …

The polymorphisms of the TNF-α gene in multiple sclerosis?—a meta-analysis

L Xu, W Yuan, H Sun, X Zhang, X Jia, C Shen… - Molecular biology …, 2011 - Springer
The association between multiple sclerosis (MS) and tumor necrosis factor-alpha gene (TNF-
α) polymorphisms has been analyzed in several studies, but conflicting results have been …

[HTML][HTML] Association between tumor necrosis factor-α-308 G/A polymorphism and multiple sclerosis: a systematic review and meta-analysis

H Tolide-Ie, HR Tabatabaee… - Iranian Journal of …, 2014 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is a complex polygenic disease in which gene-environment
interactions are important. A number of studies have investigated the association between …

Association of polymorphism -308G/A in tumor necrosis factor-alpha gene (TNF-α) and TNF-α serum levels in patients with relapsing-remitting multiple sclerosis

AA Grigorova, AG Trenova, SA Stanilova - Neurological Research, 2021 - Taylor & Francis
ABSTRACT TNF-α is an important cytokine of the inflammatory response involved in the
pathogenesis of relapsing-remitting multiple sclerosis (RRMS). The aim of this study is to …

Decreased frequency of the tumor necrosis factor α–308 allele in Serbian patients with multiple sclerosis

J Drulović, D Popadić, Š Mesaroš, I Dujmović… - European …, 2003 - karger.com
Tumor necrosis factor (TNF) α has been considered the prototypic cytopathogenic cytokine
in multiple sclerosis (MS), but recently this cytokine has been shown to possess significant …

Multiple sclerosis: association with the interleukin-1 gene family polymorphisms in the Turkish population

N Isik, A Arman, IA Canturk, AC Gurkan… - International Journal …, 2013 - Taylor & Francis
Background: Multiple Sclerosis (MS) is a neurodegenerative disease. It involves
inflammation and demyelination. Since cytokines play an important role in the development …

Cytokine gene polymorphisms in multiple sclerosis: a meta‐analysis of 45 studies including 7379 cases and 8131 controls

GK Nikolopoulos, A Masgala, C Tsiara… - European Journal of …, 2011 - Wiley Online Library
Many environmental and genetic factors have been implicated in the development of
multiple sclerosis. However, the aetiology has not been clarified yet. Therefore, using a meta …