The neuropeptide calcitonin gene‐related peptide is well established as a key player in the
pathogenesis of migraine. Clinical studies show calcitonin gene‐related peptide levels …

Background The clinical efficacy of migraine therapeutic agents directed towards the
calcitonin-gene related peptide (CGRP) pathway has confirmed the key role of this axis in …

Calcitonin gene-related peptide (CGRP) is a potent neuromodulator and vasodilator. It has
been implicated in the pathogenesis of migraine by a number of lines of evidence, although …

Migraine is a common neurologic disorder characterized by attacks consisting of unilateral,
throbbing headache accompanied by photophobia, phonophobia, and nausea which …

Abstract Treatment of migraine is on the cusp of a new era with the development of drugs
that target the trigeminal sensory neuropeptide calcitonin gene-related peptide (CGRP) or its …

Migraine is a common neurological disorder that afflicts up to 15% of the adult population in
most countries, with predominance in females. It is characterized by episodic, often disabling …

Several lines of evidence pointed to an important role for CGRP in migraine. These included
the anatomic colocalization of CGRP and its receptor in sensory fibers innervating pain …

Calcitonin gene‐related peptide (CGRP) is linked to migraine and other primary headache
disorders. It is found in every location described in migraine genesis and processing …

Importance of the field: Migraine is a highly prevalent disabling condition, and the current
treatment options are not satisfactory. The role of calcitonin gene-related peptide (CGRP) in …

Abstract Calcitonin Gene-Related Peptide (CGRP) plays a pivotal role in migraine
pathophysiology. Two types of CGRP function-blocking modalities, monoclonal antibodies …