Drug delivery to macrophages: A review of nano-therapeutics targeted approach for inflammatory disorders and cancer

M Mukhtar, H Ali, N Ahmed, R Munir… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

Advancements in macrophage-targeted drug delivery for effective disease management

H Liu, H Lv, X Duan, Y Du, Y Tang… - International Journal of …, 2023 - Taylor & Francis
Macrophages play a crucial role in tissue homeostasis and the innate immune system. They
perform essential functions such as presenting antigens, regulating cytokines, and …

Harnessing anti-inflammatory pathways and macrophage nano delivery to treat inflammatory and fibrotic disorders

A Zaid, A Ariel - Advanced Drug Delivery Reviews, 2024 - Elsevier
Targeting specific organs and cell types using nanotechnology and sophisticated delivery
methods has been at the forefront of applicative biomedical sciences lately. Macrophages …

Nanomedicines for dysfunctional macrophage-associated diseases

H He, S Ghosh, H Yang - Journal of Controlled Release, 2017 - Elsevier
Macrophages play vital functions in host inflammatory reaction, tissue repair, homeostasis
and immunity. Dysfunctional macrophages have significant pathophysiological impacts on …

Macrophages as promising carriers for nanoparticle delivery in anticancer therapy

A Wróblewska, A Szczygieł… - International Journal …, 2023 - Taylor & Francis
Macrophages play a critical role in the immune response due to their ability to recognize and
remove pathogens, as well as present antigens, which are involved in inflammation, but they …

Interactions with the macrophages: an emerging targeted approach using novel drug delivery systems in respiratory diseases

M Mehta, N Sharma, M Vyas, N Khurana… - Chemico-biological …, 2019 - Elsevier
Macrophages are considered as the most flexible cells of the hematopoietic system that are
distributed in the tissues to act against pathogens and foreign particles. Macrophages are …

Recent advances in macrophage-mediated drug delivery systems

T Liang, R Zhang, X Liu, Q Ding, S Wu… - International journal …, 2021 - Taylor & Francis
Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …

Nanoparticles targeting macrophages as potential clinical therapeutic agents against cancer and inflammation

G Hu, M Guo, J Xu, F Wu, J Fan, Q Huang… - Frontiers in …, 2019 - frontiersin.org
With the development of nanotechnology, significant progress has been made in the design,
and manufacture of nanoparticles (NPs) for use in clinical treatments. Recent increases in …

Nanoparticle‐laden macrophages for tumor‐tropic drug delivery

W Zhang, M Wang, W Tang, R Wen, S Zhou… - Advanced …, 2018 - Wiley Online Library
Macrophages hold great potential in cancer drug delivery because they can sense
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …

Macrophage membrane coated nanoparticles: a biomimetic approach for enhanced and targeted delivery

N Khatoon, Z Zhang, C Zhou, M Chu - Biomaterials science, 2022 - pubs.rsc.org
The enhanced and targeted drug delivery with low systemic toxicity and subsequent release
of drugs is a major concern among researchers and pharmaceutics. In spite of greater …