An activatable nanoenzyme reactor for coenhanced chemodynamic and starving therapy against tumor hypoxia and antioxidant defense system

Z Qing, A Bai, L Chen, S Xing, Z Zou, Y Lei, J Li… - CCS …, 2021 - chinesechemsoc.org
It is critical to improve the efficiency of cancer therapy with minimized side effects.
Chemodynamic therapy (CDT) is a tumor therapeutic strategy designed to generate …

Engineered Magnetic Polymer Nanoparticles Can Ameliorate Breast Cancer Treatment Inducing Pyroptosis–Starvation along with Chemotherapy

Y Liu, K Guo, M Ding, B Zhang, N Xiao… - … Applied Materials & …, 2022 - ACS Publications
Nanotechnology has shown a revolution in cancer treatments, including breast cancers.
However, there remain some challenges and translational hurdles. Surgery, radiotherapy …

Biomimetic CoO@ AuPt nanozyme responsive to multiple tumor microenvironmental clues for augmenting chemodynamic therapy

S Fu, R Yang, L Zhang, W Liu, G Du, Y Cao, Z Xu… - Biomaterials, 2020 - Elsevier
Chemodynamic therapy (CDT), an emerging therapeutic strategy, has been recently
exploited for in situ treatment through Fenton or Fenton-like reactions to generate cytotoxic …

Multifunctional nanoparticles loaded with vascular endothelial growth factor inhibitors and MED1 siRNA to inhibit breast cancer progression by targeting tumor …

S Wang, Z Luo, X Zhou, C Wang, Y Luo… - Journal of …, 2021 - ingentaconnect.com
Breast cancer is still threatening many people'lives, hence novel targeted therapies are
urgently required to improve the poor outcome of breast cancer patients. Herein, our study …

Nano‐gold micelles loaded Dox and Elacridar for reversing drug resistance of breast cancer

LJ Wen, YS Wang, J Zhang - IET nanobiotechnology, 2023 - Wiley Online Library
The aim of this study was to provide a new effective carrier for rescuing the sensitivity of drug‐
resistant in breast cancer cells. Nano‐gold micelles loaded with Dox and Elacridar (FP …

[HTML][HTML] Ignored role of polyphenol in boosting reactive oxygen species generation for polyphenol/chemodynamic combination therapy

H Mao, Y Wen, Y Yu, H Li, J Wang, B Sun - Materials Today Bio, 2022 - Elsevier
Chemodynamic therapy (CDT) is a promising tumor-specific treatment, but still suffering
insufficient reactive oxygen species (ROS) levels due to its limited efficacy of Fenton/Fenton …

Therapeutic potentials of FexMoyS-PEG nanoparticles in colorectal cancer: a multimodal approach via ROS-ferroptosis-glycolysis regulation

Z Yu, C Wang, Y Ye, S Wang, K Jiang - Journal of Nanobiotechnology, 2024 - Springer
Improving cancer therapy by targeting the adverse tumor microenvironment (TME) rather
than the cancer cells presents a novel and potentially effective strategy. In this study, we …

Cocktail strategy based on spatio‐temporally controlled nano device improves therapy of breast cancer

T Lang, Y Liu, Z Zheng, W Ran, Y Zhai, Q Yin… - Advanced …, 2019 - Wiley Online Library
Metastatic breast cancer may be resistant to chemo‐immunotherapy due to the existence of
cancer stem cells (CSC). Also, the control of particle size and drug release of a drug carrier …

A NIR‐II Photoactivatable “ROS Bomb” with High‐Density Cu2O‐Supported MoS2 Nanoflowers for Anticancer Therapy

J Huang, G Deng, S Wang, T Zhao, Q Chen… - Advanced …, 2023 - Wiley Online Library
The fast conversion of hydrogen peroxide (H2O2) into reactive oxygen species (ROS) at
tumor sites is a promising anticancer strategy by manipulating nanomedicines with near …

A spark to the powder keg: Microneedle-based antitumor nanomedicine targeting reactive oxygen species accumulation for chemodynamic/photothermal …

K Liao, B Niu, H Dong, L He, Y Zhou, Y Sun… - Journal of Colloid and …, 2022 - Elsevier
Hypothesis. Chemodynamic therapy (CDT) can efficiently kill cancer cells by producing
hydroxyl radical (• OH), a kind of high-toxic reactive oxygen species (ROS), via Fenton or …