At present, due to its wide application and relatively low cost, chemotherapy remains a
clinically important cancer treatment option; however, a number of chemotherapeutic drugs …

Hypothesis. Chemodynamic therapy (CDT) can efficiently kill cancer cells by producing
hydroxyl radical (• OH), a kind of high-toxic reactive oxygen species (ROS), via Fenton or …

Chemotherapy remains the primary treatment for tumors due to its systemic tumor-
suppressing ability. However, the efficacy of chemotherapy is limited by drug resistance in …

Triple-negative breast cancer (TNBC) remains the second most-life-threatening carcinoma
to women worldwide. Compared to conventional chemotherapeutic drugs, natural …

Triple negative breast cancer (TNBC) is an aggressive form of tumor, more prevalent in
younger women resulting in poor survival rate (2nd in cancer deaths) because of its …

The poor drug delivery and unsatisfying therapeutic effects remain to be the primary
challenges for cancer therapy. Nanosystem that combines multiple functions into a single …

Nitric oxide (NO) molecular messenger can reverse the multidrug resistance (MDR) effect of
cancer cells through reducing P-glycoprotein (P-gp) expression, beneficial for creating a …

Fenton cancer therapy as a new methodology for the treatment of tumour cells is largely
restricted owing to the low stability, high aggregation, and poor selectivity of reported …

Chemodynamic therapy (CDT) efficacy has been limited by the poor penetration ability of
large nanoparticles (NPs) and the antioxidant activity of tumors, especially high heme …

The most important aspect of chemodynamic therapy (CDT) is the harnessing of Fenton or
Fenton-like chemistry for cancer therapy within the tumor microenvironment, which occurs …