Virological failure and HIV-1 drug resistance mutations among naive and antiretroviral pre-treated patients entering the ESTHER program of Calmette Hospital in …
H Barennes, S Guillet, S Limsreng, S Him, J Nouhin… - PloS one, 2014 - journals.plos.org
Introduction In resource limited settings, patients entering an antiretroviral therapy (ART)
program comprise ART naive and ART pre-treated patients who may show differential …
program comprise ART naive and ART pre-treated patients who may show differential …
Prevalence of pretreatment HIV drug resistance in Cameroon following a nationally representative WHO survey
GF Tchouwa, S Eymard-Duvernay… - Journal of …, 2018 - academic.oup.com
Background Pretreatment HIV drug resistance (PDR) has the potential to affect treatment
outcome and mortality. We present here the first nationally representative PDR study …
outcome and mortality. We present here the first nationally representative PDR study …
Implementation of an intensive adherence intervention in patients with second-line antiretroviral therapy failure in four west African countries with little access to …
SP Eholie, R Moh, A Benalycherif, D Gabillard… - The Lancet …, 2019 - thelancet.com
Background The decision about whether to switch to third-line antiretroviral therapy (ART) in
patients with treatment failure on second-line therapy is difficult in settings with little access …
patients with treatment failure on second-line therapy is difficult in settings with little access …
Drivers of HIV-1 drug resistance to non-nucleoside reverse-transcriptase inhibitors (NNRTIs) in nine southern African countries: a modelling study
Introduction The rise of HIV-1 drug resistance to non-nucleoside reverse-transcriptase
inhibitors (NNRTI) threatens antiretroviral therapy's long-term success (ART). NNRTIs will …
inhibitors (NNRTI) threatens antiretroviral therapy's long-term success (ART). NNRTIs will …
HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa
K Steegen, M Bronze… - Journal of …, 2016 - academic.oup.com
Background Routine HIV-1 antiretroviral drug resistance testing for patients failing NNRTI-
based regimens is not recommended in resource-limited settings. Therefore, surveys are …
based regimens is not recommended in resource-limited settings. Therefore, surveys are …
Heavily treatment-experienced people living with HIV in the OPERA® cohort: population characteristics and clinical outcomes
RK Hsu, JS Fusco, CE Henegar, V Vannappagari… - BMC Infectious …, 2023 - Springer
Background Multi-class resistance, intolerance, and drug–drug interactions can result in
unique antiretroviral (ART) combinations for heavily treatment-experienced (HTE) people …
unique antiretroviral (ART) combinations for heavily treatment-experienced (HTE) people …
High viral load and multidrug resistance due to late switch to second-line regimens could be a major obstacle to reach the 90-90-90 UNAIDS objectives in sub …
E Guichet, A Aghokeng, L Serrano, G Bado… - AIDS Research and …, 2016 - liebertpub.com
In the context of lifelong antiretroviral treatment (ART) as early as possible and to end the
HIV/AIDS epidemic as a public health treat by 2030, it is important to evaluate the potential …
HIV/AIDS epidemic as a public health treat by 2030, it is important to evaluate the potential …
Resistance profiles after different periods of exposure to a first-line antiretroviral regimen in a Cameroonian cohort of HIV type-1-infected patients
A Soria, K Porten, JC Fampou-Toundji… - Antiviral …, 2009 - journals.sagepub.com
Background The lack of HIV type-1 (HIV-1) viral load (VL) monitoring in resource-limited
settings might favour the accumulation of resistance mutations and thus hamper second-line …
settings might favour the accumulation of resistance mutations and thus hamper second-line …
Pre-treatment HIV-drug resistance associated with virologic outcome of first-line NNRTI-antiretroviral therapy: a cohort study in Kenya
IA Beck, M Levine, CJ McGrath, S Bii, RS Milne… - …, 2020 - thelancet.com
Background Pre-treatment HIV-drug-resistance (PDR) to WHO-recommended 1st-line non-
nucleoside reverse transcriptase inhibitors (NNRTI)-based antiretroviral treatment (ART) is …
nucleoside reverse transcriptase inhibitors (NNRTI)-based antiretroviral treatment (ART) is …
Choice of initial antiretroviral drugs and treatment outcomes among HIV-infected patients in sub-Saharan Africa: systematic review and meta-analysis of observational …
Background The effectiveness of antiretroviral therapy (ART) depends on the choice of
regimens during initiation. Most evidences from developed countries indicated that there is …
regimens during initiation. Most evidences from developed countries indicated that there is …