Monocyte transmodulation: the next novel therapeutic approach in overcoming ischemic stroke?
J Park, JY Chang, JY Kim, JE Lee - Frontiers in neurology, 2020 - frontiersin.org
The immune response following neuroinflammation is a vital element of ischemic stroke
pathophysiology. After the onset of ischemic stroke, a specialized vasculature system that …
pathophysiology. After the onset of ischemic stroke, a specialized vasculature system that …
Reparative system arising from CCR2 (+) monocyte conversion attenuates neuroinflammation following ischemic stroke
J Park, JY Kim, YR Kim, M Huang, JY Chang… - Translational Stroke …, 2021 - Springer
Monocytes recruitment from the blood to inflamed tissues following ischemic stroke is an
important immune response to wound healing and tissue repair. Mouse monocytes can be …
important immune response to wound healing and tissue repair. Mouse monocytes can be …
The role of monocytes in ischemic stroke pathobiology: new avenues to explore
A ElAli, N Jean LeBlanc - Frontiers in aging neuroscience, 2016 - frontiersin.org
Ischemic stroke accounts for the majority of stroke cases and constitutes a major cause of
death and disability in the industrialized world. Inflammation has been reported to constitute …
death and disability in the industrialized world. Inflammation has been reported to constitute …
Macrophage and monocyte subsets in response to ischemic stroke
N Blank‐Stein, E Mass - European Journal of Immunology, 2023 - Wiley Online Library
Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …
stroke research, the only pharmacological treatment currently available is arterial …
[HTML][HTML] Is immunomodulation a principal mechanism underlying how cell-based therapies enhance stroke recovery?
Inflammation within the brain and in peripheral tissues contributes to brain injury following
ischemic stroke. Therapeutic modulation of the inflammatory response has been actively …
ischemic stroke. Therapeutic modulation of the inflammatory response has been actively …
The translational potential of microglia and monocyte-derived macrophages in ischemic stroke
The immune response to ischemic stroke is an area of study that is at the forefront of stroke
research and presents promising new avenues for treatment development. Upon cerebral …
research and presents promising new avenues for treatment development. Upon cerebral …
[HTML][HTML] Stem cell–based immunomodulation after stroke
MCS Boshuizen, GK Steinberg - Stroke, 2018 - journals.lww.com
Stroke is a major cause of death and disability worldwide. The inflammatory response is
pivotal to the pathophysiology of ischemic stroke. It begins in the vasculature directly after …
pivotal to the pathophysiology of ischemic stroke. It begins in the vasculature directly after …
Macrophages reprogram after ischemic stroke and promote efferocytosis and inflammation resolution in the mouse brain
W Zhang, J Zhao, R Wang, M Jiang… - CNS neuroscience & …, 2019 - Wiley Online Library
Aims Blood‐borne monocytes/macrophages infiltrate the brain in massive numbers after
ischemic stroke, but their impact on poststroke brain injury and recovery remains elusive …
ischemic stroke, but their impact on poststroke brain injury and recovery remains elusive …
The involvement and therapy target of immune cells after ischemic stroke
Z Jian, R Liu, X Zhu, D Smerin, Y Zhong, L Gu… - Frontiers in …, 2019 - frontiersin.org
After ischemic stroke, the integrity of the blood-brain barrier is compromised. Peripheral
immune cells, including neutrophils, T cells, B cells, dendritic cells, and macrophages …
immune cells, including neutrophils, T cells, B cells, dendritic cells, and macrophages …
Inflammatory mechanisms in ischemic stroke: therapeutic approaches
SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
most frequent cause of permanent disability in adults worldwide. Despite advances in the …