HR Angelo, D. Askgaard, IC Bygbjerg, AM Rønn. Centre for International Health and
Development, Faculty of Health Sciences, University of Copenhagen DK-1353 …

HR Angelo, D. Askgaard, IC Bygbjerg, AM Rønn. Centre for International Health and
Development, Faculty of Health Sciences, University of Copenhagen DK-1353 …

Therapeutic drug monitoring of tacrolimus by high-performance liquid chromatography–
tandem mass spectrometry has become standard practice. We report on the long-term (4.5 …

The authors describe a highly selective liquid chromatographic/mass spectrometric (LC/MS)
method for measurement of the immunosuppressive drug tacrolimus. A protein-free …

An HPLC/MS/MS assay for tacrolimus in whole blood using FR900520 as an internal
standard was validated over the standard curve range of 0.100–10.040 ng ml− 1. The …

Tacrolimus (Prograf®) is a potent immunosuppressive agent for the prevention of organ
rejection. Extreme inter-and intra-patient variability and lack of correlation between drug …

BACKGROUND: Tacrolimus, an immunosuppressive drug discovered in 1984, is used to
decrease the risk of organ rejection. The 2007 European Consensus Conference on …

Values are the mean of measurements obtained in triplicate.* Reference concentrations for
QC samples were 5.4, 11.9, and 19.2 ng/mL for low, medium, and high levels, respectively …

Tacrolimus is a commonly used immunosuppressive agent in organ transplant recipients.
Therapeutic drug monitoring (TDM) of tacrolimus is essential to adjust the dose and achieve …

Background: The immunosuppressive drug tacrolimus has complex and unpredictable
pharmacokinetics, therefore regular monitoring is required in patients receiving tacrolimus …