PGS scaffolds promote the in vivo survival and directional differentiation of bone marrow mesenchymal stem cells restoring the morphology and function of wounded …

B Xiao, W Yang, D Lei, J Huang, Y Yin… - Advanced …, 2019 - Wiley Online Library
Intrauterine adhesion (IUA) causing infertility and recurrent miscarriage of reproductive
female mammals usually results from endometrium injury. Nevertheless, there is no efficient …

Transplantation of bone marrow mesenchymal stem cells on collagen scaffolds for the functional regeneration of injured rat uterus

L Ding, H Sun, J Su, N Lin, B Péault, T Song, J Yang… - Biomaterials, 2014 - Elsevier
Serious injuries of endometrium in women of reproductive age are often followed by uterine
scar formation and a lack of functional endometrium predisposing to infertility or miscarriage …

An acellular scaffold facilitates endometrial regeneration and fertility restoration via recruiting endogenous mesenchymal stem cells

L Xin, X Zheng, J Chen, S Hu, Y Luo… - Advanced …, 2022 - Wiley Online Library
Severe intrauterine adhesions (IUAs), characterized by inadequate endometrial repair and
fibrosis, can lead to infertility. Stem cell‐based therapies, which deliver mesenchymal stem …

A collagen scaffold loaded with human umbilical cord-derived mesenchymal stem cells facilitates endometrial regeneration and restores fertility

L Xin, X Lin, Y Pan, X Zheng, L Shi, Y Zhang, L Ma… - Acta biomaterialia, 2019 - Elsevier
In women of reproductive age, severe injuries to the endometrium are often accompanied by
endometrial scar formation or intrauterine adhesions (IUAs), which can result in infertility or …

Human amniotic mesenchymal stem cells combined with PPCNg facilitate injured endometrial regeneration

J Huang, W Zhang, J Yu, Y Gou, N Liu, T Wang… - Stem Cell Research & …, 2022 - Springer
Background Caused by the injury to the endometrial basal layer, intrauterine adhesions
(IUA) are characterized by uterine cavity obliteration, leading to impaired fertility. Human …

[HTML][HTML] Recent developments in bio-scaffold materials as delivery strategies for therapeutics for endometrium regeneration

X Li, HF Lv, R Zhao, M Ying, AT Samuriwo, YZ Zhao - Materials Today Bio, 2021 - Elsevier
Intrauterine adhesions (IUAs) refer to the repair disorder after endometrial injury and may
lead to uterine infertility, recurrent miscarriage, abnormal menstrual bleeding, and other …

[HTML][HTML] Vascular remodeling by placenta-derived mesenchymal stem cells restores ovarian function in ovariectomized rat model via the VEGF pathway

J Cho, TH Kim, J Seok, JH Jun, H Park, M Kweon… - Laboratory …, 2021 - Elsevier
Angiogenesis plays an important role in damaged organ or tissue and cell regeneration and
ovarian development and function. Primary ovarian insufficiency (POI) is a prevalent …

Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro

X Li, Y Wang, R Ma, X Liu, B Song, Y Duan… - Biomedical …, 2021 - iopscience.iop.org
Infertile people who suffered from loss of uterine structures and/or functions can be treated
through gestational surrogacy or uterus transplantation, which remains challenging due to …

3D-cultured human placenta-derived mesenchymal stem cell spheroids enhance ovary function by inducing folliculogenesis

TH Kim, JH Choi, Y Jun, SM Lim, S Park, JY Paek… - Scientific reports, 2018 - nature.com
Placenta-derived mesenchymal stem cells (PD-MSCs) have numerous advantages over
other adult MSCs that make them an attractive cell source for regenerative medicine. Here …

Bone marrow mesenchymal stem cells combined with estrogen synergistically promote endometrial regeneration and reverse EMT via Wnt/β-catenin signaling …

L Yuan, J Cao, M Hu, D Xu, Y Li, S Zhao, J Yuan… - Reproductive Biology …, 2022 - Springer
Background Intrauterine adhesion (IUA) is a clinical disease characterized by the uterine
cavity occlusion caused by the damage of the endometrial basal layer. Bone marrow …