Testosterone augments polyphenol‐induced DNA damage response in prostate cancer cell line, LNCaP

H Ide, J Yu, Y Lu, T China, T Kumamoto… - Cancer …, 2011 - Wiley Online Library
Recently, we reported that combined ingestion of soy isoflavones and curcumin significantly
decreased the serum level of prostate‐specific antigen based on a randomized placebo …

[HTML][HTML] Chemoprevention of prostate cancer: soy isoflavones and curcumin

S Horie - Korean Journal of Urology, 2012 - synapse.koreamed.org
The burden of increasing morbidity and mortality due to prostate cancer imposes a need for
new, effective measures of prevention in daily life. The influence of lifestyle on …

Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IκBα, c-Jun and androgen receptor

H Guo, YM Xu, ZQ Ye, JH Yu… - Die Pharmazie-An …, 2013 - ingentaconnect.com
Curcumin possesses chemopreventive properties against several types of cancer, but the
molecular mechanisms by which it induces apoptosis of cancer cells and inhibits cancer cell …

Combination treatment of prostate cancer cell lines with bioactive soy isoflavones and perifosine causes increased growth arrest and/or apoptosis

RL Vinall, K Hwa, P Ghosh, CX Pan, PN Lara Jr… - Clinical Cancer …, 2007 - AACR
Purpose: To determine whether targeting the androgen receptor (AR) and Akt pathways
using a combination of genistein combined polysaccharide (GCP) and perifosine is more …

Curcumin blocks the activation of androgen and interlukin‐6 on prostate‐specific antigen expression in human prostatic carcinoma cells

KH Tsui, TH Feng, CM Lin, PL Chang… - Journal of …, 2008 - Wiley Online Library
Curcumin, a naturally occurring compound, exhibits anticancer chemopreventive effects. We
evaluated the effects and mechanisms of curcumin on the gene expression of prostate …

Genistein protects prostate cells against hydrogen peroxide-induced DNA damage and induces expression of genes involved in the defence against oxidative stress

M Raschke, IR Rowland, PJ Magee… - …, 2006 - academic.oup.com
Prostate cancer is one of the most frequent cancer types in Western societies and
predominately occurs in the elderly male. The strong age-related increase of prostate cancer …

Effects of phytoestrogens on growth and DNA integrity in human prostate tumor cell lines: PC-3 and LNCaP

JH Mitchell, SJ Duthie, AR Collins - Nutrition and cancer, 2000 - Taylor & Francis
Prostate cancer is one of the most common male cancers in Western countries, yet the
incidence of this fatal disease remains low in Asian populations. Environmental factors such …

[PDF][PDF] Inhibitory effect of isoflavones on prostate cancer cells and PTEN gene

F Cao, T Jin, Y Zhou - Biomedical and Environmental Sciences, 2006 - besjournal.com
Objective To explore the mechanisms by which genistein and daidzein inhibit the growth of
prostate cancer cells. Methods LNCaP and PC-3 cells were exposed to genistein and …

Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate‐specific antigen

H Ide, S Tokiwa, K Sakamaki, K Nishio, S Isotani… - The …, 2010 - Wiley Online Library
BACKGROUND Sustained chronic inflammation in the prostate promotes prostate
carcinogenesis. Since an elevated level of prostate‐specific antigen (PSA) per se reflects …

Radiation‐induced HIF‐1α cell survival pathway is inhibited by soy isoflavones in prostate cancer cells

V Singh‐Gupta, H Zhang, S Banerjee… - … journal of cancer, 2009 - Wiley Online Library
We previously showed that treatment of prostate cancer cells with soy isoflavones and
radiation resulted in greater cell killing in vitro, and caused downregulation of NF‐κB and …