Carbon monoxide (CO) is generated during incomplete combustion of carbon-containing
compounds and leads to acute and chronic toxicity in animals and humans depending on …

▪ Abstract Many biological functions of heme oxygenase (HO), such as cytoprotection
against oxidative stress, vasodilation, neurotransmission in the central or peripheral nervous …

In this review, we address the regulatory and toxic role of· NO along several pathways, from
the gut to the brain. Initially, we address the role on· NO in the regulation of mitochondrial …

Carbon monoxide (CO) has long been primarily viewed as a toxic gas because of its strong
affinity for hemoglobin.[1, 2] However, the biological function of carbon monoxide and its …

Aims: In this original research communication, we assess the impact of shifting the window
of glial HMOX1 overexpression in mice from early-to-midlife to mid-to-late life, resulting in …

Dopamine signaling has numerous roles during brain development. In addition, alterations
in dopamine signaling may be also involved in the pathophysiology of psychiatric disorders …

Modulation of cerebral cell metabolism for improving the outcome of hypoxia-ischemia and
reperfusion is a strategy yet to be explored. Because carbon monoxide (CO) is known to …

The toxic effect of high concentrations of CO gas in living organisms is coherently typified at
biochemical levels by the high affinity of CO for hemoglobin and cytochromes, heme …

Activation of neuronal nicotinic acetylcholine receptors (nAChR) provides neuroprotection
against different toxic stimuli that often lead to overproduction of reactive oxygen species …

Carbon monoxide (CO), which is classically thought of as a toxic molecule and cellular
asphyxiate, has become increasingly recognized as an important molecule in the …