Bench-to-bedside review: carbon monoxide–from mitochondrial poisoning to therapeutic use
I Bauer, BHJ Pannen - Critical Care, 2009 - Springer
Carbon monoxide (CO) is generated during incomplete combustion of carbon-containing
compounds and leads to acute and chronic toxicity in animals and humans depending on …
compounds and leads to acute and chronic toxicity in animals and humans depending on …
CO as a cellular signaling molecule
HP Kim, SW Ryter, AMK Choi - Annu. Rev. Pharmacol. Toxicol., 2006 - annualreviews.org
▪ Abstract Many biological functions of heme oxygenase (HO), such as cytoprotection
against oxidative stress, vasodilation, neurotransmission in the central or peripheral nervous …
against oxidative stress, vasodilation, neurotransmission in the central or peripheral nervous …
The peculiar facets of nitric oxide as a cellular messenger: from disease-associated signaling to the regulation of brain bioenergetics and neurovascular coupling
In this review, we address the regulatory and toxic role of· NO along several pathways, from
the gut to the brain. Initially, we address the role on· NO in the regulation of mitochondrial …
the gut to the brain. Initially, we address the role on· NO in the regulation of mitochondrial …
[PDF][PDF] A selective fluorescent probe for carbon monoxide imaging in living cells
J Wang, J Karpus, BS Zhao, Z Luo… - Angewandte Chemie …, 2012 - researchgate.net
Carbon monoxide (CO) has long been primarily viewed as a toxic gas because of its strong
affinity for hemoglobin.[1, 2] However, the biological function of carbon monoxide and its …
affinity for hemoglobin.[1, 2] However, the biological function of carbon monoxide and its …
Strategic Timing of Glial HMOX1 Expression Results in Either Schizophrenia-Like or Parkinsonian Behavior in Mice
Aims: In this original research communication, we assess the impact of shifting the window
of glial HMOX1 overexpression in mice from early-to-midlife to mid-to-late life, resulting in …
of glial HMOX1 overexpression in mice from early-to-midlife to mid-to-late life, resulting in …
[HTML][HTML] Dopamine signaling impairs ROS modulation by mitochondrial hexokinase in human neural progenitor cells
G Assis-de-Lemos, J Monteiro… - Bioscience …, 2021 - portlandpress.com
Dopamine signaling has numerous roles during brain development. In addition, alterations
in dopamine signaling may be also involved in the pathophysiology of psychiatric disorders …
in dopamine signaling may be also involved in the pathophysiology of psychiatric disorders …
Carbon monoxide modulates apoptosis by reinforcing oxidative metabolism in astrocytes
AS Almeida, CSF Queiroga, MFQ Sousa… - Journal of Biological …, 2012 - ASBMB
Modulation of cerebral cell metabolism for improving the outcome of hypoxia-ischemia and
reperfusion is a strategy yet to be explored. Because carbon monoxide (CO) is known to …
reperfusion is a strategy yet to be explored. Because carbon monoxide (CO) is known to …
Mitochondrial and cellular heme-dependent proteins as targets for the bioactive function of the heme oxygenase/carbon monoxide system
M Desmard, J Boczkowski, J Poderoso… - Antioxidants & Redox …, 2007 - liebertpub.com
The toxic effect of high concentrations of CO gas in living organisms is coherently typified at
biochemical levels by the high affinity of CO for hemoglobin and cytochromes, heme …
biochemical levels by the high affinity of CO for hemoglobin and cytochromes, heme …
Nicotinic receptor activation by epibatidine induces heme oxygenase‐1 and protects chromaffin cells against oxidative stress
Activation of neuronal nicotinic acetylcholine receptors (nAChR) provides neuroprotection
against different toxic stimuli that often lead to overproduction of reactive oxygen species …
against different toxic stimuli that often lead to overproduction of reactive oxygen species …
Carbon monoxide: medicinal chemistry and biological effects
DJ Kaczorowski, BS Zuckerbraun - Current medicinal chemistry, 2007 - ingentaconnect.com
Carbon monoxide (CO), which is classically thought of as a toxic molecule and cellular
asphyxiate, has become increasingly recognized as an important molecule in the …
asphyxiate, has become increasingly recognized as an important molecule in the …