Reactive oxygen species in the regulation of the GABA mediated inhibitory neurotransmission
ANB González, MIL Pazos, DJ Calvo - Neuroscience, 2020 - Elsevier
Reactive oxygen species (ROS) are best known for being involved in cellular metabolism
and oxidative stress, but also play important roles in cell communication. ROS signaling has …
and oxidative stress, but also play important roles in cell communication. ROS signaling has …
Carbon monoxide improves neuronal differentiation and yield by increasing the functioning and number of mitochondria
AS Almeida, U Sonnewald, PM Alves… - Journal of …, 2016 - Wiley Online Library
The process of cell differentiation goes hand‐in‐hand with metabolic adaptations, which are
needed to provide energy and new metabolites. Carbon monoxide (CO) is an endogenous …
needed to provide energy and new metabolites. Carbon monoxide (CO) is an endogenous …
Heme oxygenase and carbon monoxide initiate homeostatic signaling
M Bilban, A Haschemi, B Wegiel, BY Chin… - Journal of Molecular …, 2008 - Springer
Carbon monoxide (CO), a gaseous second messenger, arises in biological systems during
the oxidative catabolism of heme by the heme oxygenase (HO) enzymes. Many biological …
the oxidative catabolism of heme by the heme oxygenase (HO) enzymes. Many biological …
Adaptive potential of the heme oxygenase/carbon monoxide pathway during hypoxia
MS Tift, RW Alves de Souza, J Weber… - Frontiers in …, 2020 - frontiersin.org
Heme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide
(CO) and iron into circulation. These byproducts of heme degradation can have potent …
(CO) and iron into circulation. These byproducts of heme degradation can have potent …
Heme oxygenase, a likely regulator of cGMP production in the brain: induction in vivo of HO-1 compensates for depression in NO synthase activity
MD Maines, JA Mark, JF Ewing - Molecular and Cellular Neuroscience, 1993 - Elsevier
To examine the role of carbon monoxide (CO) as a putative neuronal messenger and
regulator of cGMP level in vivo, we exploited an animal model to increase brain capability to …
regulator of cGMP level in vivo, we exploited an animal model to increase brain capability to …
Biological signaling by carbon monoxide and carbon monoxide-releasing molecules
R Motterlini, R Foresti - American Journal of Physiology …, 2017 - journals.physiology.org
Carbon monoxide (CO) is continuously produced in mammalian cells during the
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …
Carbon monoxide and human disease
D Morse, J Sethi - Antioxidants and Redox Signaling, 2002 - liebertpub.com
Carbon monoxide is produced endogenously in humans through the breakdown of
hemoglobin by heme oxygenase. Although originally thought to be a superfluous by-product …
hemoglobin by heme oxygenase. Although originally thought to be a superfluous by-product …
[HTML][HTML] Nature's marvels endowed in gaseous molecules I: carbon monoxide and its physiological and therapeutic roles
Nature has endowed gaseous molecules such as O 2, CO 2, CO, NO, H 2 S, and N 2 with
critical and diverse roles in sustaining life, from supplying energy needed to power life and …
critical and diverse roles in sustaining life, from supplying energy needed to power life and …
Carbon monoxide: an unusual drug
F Gullotta, A Masi, P Ascenzi - IUBMB life, 2012 - Wiley Online Library
The highly toxic gas carbon monoxide (CO) displays many physiological roles in several
organs and tissues. Although many diseases, including cancer, hematological diseases …
organs and tissues. Although many diseases, including cancer, hematological diseases …
Preferential heme oxygenase-1 activation in striatal astrocytes antagonizes dopaminergic neuron degeneration in MPTP-intoxicated mice
X Xu, N Song, R Wang, H Jiang, J Xie - Molecular neurobiology, 2016 - Springer
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the
substantia nigra pars compacta (SNpc) accompanied by increased oxidative damage …
substantia nigra pars compacta (SNpc) accompanied by increased oxidative damage …