Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by
Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link …

Superantigens (SAgs) are a family of potent immunostimulatory exotoxins known to be
produced by only a few bacterial pathogens, including Staphylococcus aureus. More than …

Staphylococcus aureus is a foremost bacterial pathogen responsible for a vast array of
human diseases. Staphylococcal superantigens (SAgs) constitute a family of exotoxins from …

Superantigens (SAgs) are potent microbial toxins that function to activate large numbers of T
cells in a T cell receptor (TCR) Vβ-specific manner, resulting in excessive immune system …

Staphylococcus aureus is a versatile bacterial pathogen that produces T cell-activating
toxins known as superantigens (SAgs). Although excessive immune activation by SAgs can …

Staphylococcus aureus strains that cause human diseases produce a large family of
pyrogenic toxin superantigens (SAgs). These include toxic shock syndrome toxin-1 (TSST …

Staphylococcus aureus is a robust pathogen that is capable of growing in virtually any part
of the human body, and can also survive and grow in many other species. S. aureus remains …

Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …

Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune
modulation and severe systemic illnesses such as Staphylococcus aureus toxic shock …

Superantigens (SAgs) are the most powerful T cell mitogens ever discovered.
Concentrations of less than 0· 1 pg/ml of a bacterial superantigen are sufficient to stimulate …