Spleen associated immune-response mediates brain-heart interaction after intracerebral hemorrhage

W Li, L Li, W Li, M Chopp, P Venkat, A Zacharek… - Experimental …, 2020 - Elsevier
Background and purpose Intracerebral hemorrhage (ICH) patients frequently encounter
cardiovascular complications which may contribute to increased mortality and poor long …

Immune response mediates the cardiac damage after subarachnoid hemorrhage

R Li, Q Yuan, Y Su, M Chopp, T Yan, J Chen - Experimental neurology, 2020 - Elsevier
Cardiac dysfunction is a common adverse effect of subarachnoid hemorrhage (SAH).
Autopsy of SAH patients shows immunocyte infiltration into the heart. In this study, a SAH …

[HTML][HTML] Intracerebral hemorrhage induces cardiac dysfunction in mice without primary cardiac disease

W Li, L Li, M Chopp, P Venkat, A Zacharek… - Frontiers in …, 2018 - frontiersin.org
Background: Intracerebral hemorrhage (ICH) is a life threatening stroke subtype and a
worldwide health problem. In this study, we investigate brain-heart interaction after ICH in …

Inflammatory responses mediate brain–heart interaction after ischemic stroke in adult mice

T Yan, Z Chen, M Chopp, P Venkat… - Journal of Cerebral …, 2020 - journals.sagepub.com
Stroke induces cardiac dysfunction which increases post stroke mortality and morbidity
particularly in aging population. Here, we investigated the effects of inflammatory responses …

Systemic inflammation in hemorrhagic strokes–A novel neurological sign and therapeutic target?

AR Saand, F Yu, J Chen… - Journal of Cerebral Blood …, 2019 - journals.sagepub.com
Growing evidences suggest that stroke is a systemic disease affecting many organ systems
beyond the brain. Stroke-related systemic inflammatory response and immune …

Immune response mediates cardiac dysfunction after traumatic brain injury

Q Zhao, T Yan, L Li, M Chopp, P Venkat… - Journal of …, 2019 - liebertpub.com
Cardiovascular complications are common after traumatic brain injury (TBI) and are
associated with increased morbidity and mortality. In this study, we investigated the possible …

[HTML][HTML] Organ-and cell-specific immune responses are associated with the outcomes of intracerebral hemorrhage

J Zhang, K Shi, Z Li, M Li, Y Han, L Wang… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Severe brain injury significantly influences immune responses; however, the levels at which
this influence occurs and which neurogenic pathways are involved are not well defined …

CNS-peripheral immune interactions in hemorrhagic stroke

X Li, G Chen - Journal of Cerebral Blood Flow & Metabolism, 2023 - journals.sagepub.com
Stroke is a sudden and rapidly progressing ischemic or hemorrhagic cerebrovascular
disease. When stroke damages the brain, the immune system becomes hyperactive, leading …

[HTML][HTML] The “dialogue” between central and peripheral immunity after ischemic stroke: Focus on spleen

H Yu, Y Cai, A Zhong, Y Zhang, J Zhang… - Frontiers in …, 2021 - frontiersin.org
The immune response generated by the body after the incidence of ischemic stroke, runs
through the comprehensive process of aftermath. During this process of ischemic stroke, the …

Inflammatory Response and Immune Regulation in Brain‐Heart Interaction after Stroke

L Zou, R Han - Cardiovascular Therapeutics, 2022 - Wiley Online Library
Cerebrocardiac syndrome (CCS) is one of the secondary myocardial injuries after stroke.
Cerebrocardiac syndrome may result in a poor prognosis with high mortality. Understanding …