Background Outcomes in patients with sepsis are better if initial empirical antimicrobial use
is appropriate. Several studies have shown that adherence to guidelines dictating …

Objectives To perform an audit of empirical antibiotic therapy (EAT) of sepsis at the
emergency department and to analyse the impact of an antimicrobial stewardship (AMS) …

Abstract Background The Dutch Working Party on Antibiotic Policy (SWAB) in collaboration
with relevant professional societies, has updated their evidence-based guidelines on …

BACKGROUND Early appropriate antibiotic therapy is an important component of the
Surviving Sepsis Guidelines bundles that are associated with decreased in-hospital …

Recent description of the microbiology of sepsis on the wards or information on the real-life
antibiotic choices used in sepsis is lacking. There is growing concern of the indiscriminate …

Many quality indicators for appropriate antibiotic use have been developed. We aimed to
make a systematic inventory, including the development methodology and validation …

Mortality in patients admitted with sepsis is high and the increasing incidence of infections
with multiresistant bacteria is a worldwide problem. Many hospitals have local antimicrobial …

Introduction: Severe infections in critically ill patients carry a high morbidity and mortality
rate. Given the impact of early and broad-spectrum empirical therapy in several studies and …

Objectives To develop and test a set of measures of quality of care in the process of sepsis
management, to determine the inter-rater reliability of case-note review in assessment of …

Sepsis is a major reason for preventable hospital deaths. A cluster-randomized controlled
trial on an educational intervention did not show improvements of sepsis management or …