Although several drugs revealed moderate amelioration of symptoms, none of them have
sufficient potency to prevent or reverse the progression toward Alzheimer's disease (AD) …

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases leading
to dementia. Despite research efforts, currently there are no effective pharmacotherapeutic …

Alzheimer's disease (AD) is an age-dependent neurodegenerative disease hallmarked by
Amyloid-β (Aβ) aggregation, cognitive impairment, and neuronal and synaptic loss. In this …

This study investigated effects of triterpenoids derived from Ganoderma lucidum (GLT) on
the ability to attenuate cognitive impairment and reduce oxidative stress and inflammation …

Background Millions of people around the globe are affected by Alzheimer's disease (AD).
This crippling condition has no treatment despite intensive studies. Some phytocompounds …

Aging is a major factor involved in neurological impairments, decreased anti-oxidant
activities, and enhanced neuroinflammation. D-galactose (D-gal) has been considered an …

In the present study, we investigated the cognitive improvement effects and its mechanisms
of krill oil (KO) in Aβ25–35-induced Alzheimer's disease (AD) mouse model. The Aβ25–35 …

Oxidative stress and neuroinflammation play crucial roles in aging. S-adenosylmethionine
(SAM), a popular supplement, is a potential antioxidant and candidate therapy for …

Phytomedicine based natural flavonoids have potent antioxidant, anti-inflammatory, and
neuroprotective activities against neurodegenerative diseases. The aim of the present study …

Diabetes mellitus is a chronic metabolic disease with a high prevalence in the Western
population. It is characterized by pancreas failure to produce insulin, which involves high …