[HTML][HTML] [68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction

S Bentsen, A Clemmensen, M Loft, M Flethøj… - Diagnostics, 2021 - mdpi.com
Angiogenesis is crucial in tissue repair and prevents scar tissue formation following an
ischemic event such as myocardial infarction. The ischemia induces formation of new …

[HTML][HTML] Angiogenesis PET Tracer Uptake (68Ga-NODAGA-E[(cRGDyK)]2) in Induced Myocardial Infarction in Minipigs

T Rasmussen, B Follin, J Kastrup, M Brandt-Larsen… - Diagnostics, 2016 - mdpi.com
Angiogenesis is part of the healing process following an ischemic injury and is vital for the
post-ischemic repair of the myocardium. Therefore, it is of particular interest to be able to …

[HTML][HTML] [68Ga]Ga-NODAGA-E[(cRGDyK)]2 angiogenesis PET following myocardial infarction in an experimental rat model predicts cardiac functional parameters …

S Bentsen, JK Jensen, E Christensen… - Journal of Nuclear …, 2023 - Springer
Background Angiogenesis has increasingly been a target for imaging and treatment over the
last decade. The integrin αvβ3 is highly expressed in cells during angiogenesis and are …

[HTML][HTML] Angiogenesis PET Tracer Uptake (68Ga-NODAGA-E[(cRGDyK)]2) in Induced Myocardial Infarction and Stromal Cell Treatment in Minipigs

T Rasmussen, B Follin, J Kastrup, M Brandt-Larsen… - Diagnostics, 2018 - mdpi.com
Angiogenesis is considered integral to the reparative process after ischemic injury. The αvβ3
integrin is a critical modulator of angiogenesis and highly expressed in activated endothelial …

PET imaging of angiogenesis after myocardial infarction/reperfusion using a one-step labeled integrin-targeted tracer 18F-AlF-NOTA-PRGD2

H Gao, L Lang, N Guo, F Cao, Q Quan, S Hu… - European journal of …, 2012 - Springer
Purpose The α v β 3 integrin represents a potential target for noninvasive imaging of
angiogenesis. The purpose of this study was to evaluate a novel one-step labeled integrin α …

Angiogenesis imaging in myocardial infarction using 68Ga-NOTA-RGD PET: characterization and application to therapeutic efficacy monitoring in rats

JS Eo, JC Paeng, S Lee, YS Lee, JM Jeong… - Coronary artery …, 2013 - journals.lww.com
Objective 68 Ga-NOTA-RGD PET is a newly developed molecular imaging for angiogenesis.
In this study, 68 Ga-NOTA-RGD PET was used to investigate imaging characteristics in a rat …

[HTML][HTML] [68Ga]-NODAGA-RGD Positron Emission Tomography (PET) for Assessment of Post Myocardial Infarction Angiogenesis as a Predictor for Left Ventricular …

CI Lang, P Döring, R Gäbel, P Vasudevan, H Lemcke… - Cells, 2020 - mdpi.com
Angiogenesis plays a central role in the healing process following acute myocardial
infarction. The PET tracer [68Ga]-NODAGA-RGD, which is a ligand for the αvβ3 integrin, has …

[HTML][HTML] Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography

M Grönman, M Tarkia, T Kiviniemi, P Halonen… - Journal of Translational …, 2017 - Springer
Background Radiolabeled RGD peptides detect α v β 3 integrin expression associated with
angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied …

Imaging of myocardial αvβ3 integrin expression for evaluation of myocardial injury after acute myocardial infarction

W Nammas, C Paunonen, J Teuho… - Journal of Nuclear …, 2024 - Soc Nuclear Med
[68Ga] Ga-NODAGA-Arg-Gly-Asp (RGD) is a PET tracer targeting αvβ3 integrin, which is
upregulated during angiogenesis soon after acute myocardial infarction (AMI). We …

[18F] Galacto-RGD PET demonstrates elevated myocardial αvβ3 expression in patients after myocardial infarction

M Makowski, A Keithahn, A Beer, U Ebersberger… - 2008 - Soc Nuclear Med
277 Objectives: The αvβ3 integrin is a key mediator of angiogenesis and thus may be an
important target associated with myocardial repair after ischemic injury. We evaluated …