BACKGROUND & AIMS:: Noxious inputs from somatic tissue are subject to biphasic
descending modulation from the rostroventral medulla (RVM). In the present study, we …

Descending inhibitory and facilitatory influences from the rostroventral medulla (RVM) on
responses of lumbosacral spinal neurons to noxious colorectal distension (CRD, 80 mmHg …

Background & Aims: Patients with fibromyalgia commonly have symptoms of abdominal
pain, suggesting that altered somatic afferent activity may influence visceral sensations. It is …

In patients with irritable bowel syndrome, visceral pain is evoked more readily following
distension of the colorectum. However, the identity of extrinsic afferent nerve pathway that …

The effect of acute, mid-cervical spinal cord lesions on neuronal and reflex activity evoked
by the noxious visceral stimulus, colorectal distension (CRD; 80 mmHg, 20 s), was …

Electrical stimulation of the nucleus submedius (Sm) has been shown to suppress the
viscerosomatic reflex (VSR), which is evoked by colorectal distension (CRD). We have …

The lower bowel is innervated by visceral afferents projecting to the lumbosacral and
thoracolumbar spinal segments. The present study tested the hypothesis that sensory …

In halothane-anesthetized rats, neurons stereotaxically located in the region of the
medullary lateral reticular nucleus (LRN) and responsive to urinary bladder distension …

To improve understanding of sensory processes related to visceral inflammation, the effect
of turpentine-induced inflammation on reflex (cardiovascular/visceromotor) and …

Recent clinical studies have demonstrated that a midline lesion of the dorsal columns (DC,
limited midline myelotomy) reduces pain of visceral origin in patients with pelvic cancer …