The thymic microenvironment plays a key role in the intrathymic T-cell differentiation. It is
composed of a tridimensional network of epithelial cells whose physiology is controlled by …

Intrathymic T‐cell differentiation is under the control of the thymic microenvironment, which
acts on maturing thymocytes via membrane as well as soluble products. Increasing data …

The thymus gland is a central lymphoid organ in which bone marrow-derived T cell
precursors undergo maturation, eventually leading to the migration of positively selected …

We describe herein the expression of the VLA6 complex by murine thymic epithelial cells
(TEC). The immunohistochemical distribution revealed that VLA6 is found in both thymic …

The thymus gland is a central lymphoid organ in which bone marrow-derived T cell
precursors undergo differentiation, eventually leading to migration of positively selected …

Objectives: Thyroid hormones exert immunomodulatory activities and the thymus is one of
their target organs. We previously showed that triiodothyronine (T3) modulates thymic …

Thymocytes undergo a complex process of differentiation, largely dependent on interactions
with the thymic microenvironment, a tridimensional cellular network formed by epithelial …

Interactions between thymocytes and thymic epithelial cell (TEC) can be modulated by
growth hormone via insulin-like growth factor-1 (IGF-1). In this study, we showed IGF-1 and …

The thymus is a primary lymphoid organ in which bone marrow-derived T cell precursors
undergo a complex maturation process in the context of the thymic microenvironment …

Extracellular matrix (ECM) proteins can influence cell migration and differentiation in a
variety of cell systems. Within the thymus, these molecules are heterogeneously distributed …