Objective To study the radiosensitizing potential of Berberine and the underlying mechanism
in human hepatocarcinoma (HepG2) cells. Methods HepG2 cells were challenged with X …

Berberine, an isoquinoline plant alkaloid, has been known to generate a wide variety of
biochemical and pharmacological effects. In order to elucidate the molecular mechanism for …

Radiation therapy is a major treatment in hepatocellular carcinoma (HCC). Yet, this
treatment is ineffective in HCC due to lack of radiosensitivity. For this reason, we examined …

PURPOSE: Radiotherapy is the most efficacious strategies for lung cancer. The radiation-
enhancing effects and the underlying mechanisms of berberine were investigated both in …

The natural alkaloid berberine has several pharmacological properties and recently
received attention as a potential anticancer agent. In this work, we investigated the …

Extensive studies have revealed that berberine, a small molecule derived from Coptidis
rhizoma (Huanglian in Chinese) and many other plants, has strong anti‐tumor properties. To …

Current chemotherapeutic strategies for liver cancer have limitations. Thus, the demand for
complementary medicine is warranted. We evaluated the antitumor potential of berberine, a …

Evidence has accumulated that berberine is able to induce cell cycle arrest and apoptosis in
many human cancer cell lines. However, there is no available information on the effects of …

Berberine (BBR) has been suggested as a potential candidate anticancer agent due to its
high anticancer activity and multiple mechanisms. In the present study, the inhibitory effect of …

Chemotherapy and radiotherapy are mainstay treatments for cancer patients. However, their
clinical outcomes are highly limited by the resistance of malignant tumors to these therapies …