This article reviews recent molecular dynamics simulations of the Alzheimer's amyloid-β
protein, the primary component of the amyloid plaques found in the brain of Alzheimer's …

Computational tools are increasingly being applied to solve the protein aggregation
problem, providing insight into amyloid structures and aggregation mechanisms. The …

A major hallmark of Alzheimer's disease (AD) is the aggregation of amyloid-β peptides in the
brains of people afflicted by the disease. The exact pathway to this catastrophic event is …

Amyloid proteins are characterized by their tendency to aggregate into amyloid fibrils, which
are often associated with devastating diseases. Aggregation pathways typically involve …

The cause of Alzheimer's disease is related to aggregates such as oligomers and amyloid
fibrils consisting of amyloid-β (Aβ) peptides. Molecular dynamics (MD) simulation studies …

The pathogenic aggregation of the amyloid β-peptide (Aβ) is considered a hallmark of the
progression of Alzheimer's disease, the leading cause of senile dementia in the elderly and …

Protein aggregation into highly structured amyloid fibrils is associated with various diseases
including Alzheimer's disease, Parkinson's disease, and type II diabetes. Amyloids can also …

Several neurodegenerative disorders arise from the abnormal protein aggregation in the
nervous tissue leading tointracellular inclusions or extracellular aggregates in specific brain …

In amyloid aggregation diseases soluble proteins coalesce into a wide array of undesirable
structures, ranging through oligomers and prefibrillar assemblies to highly ordered amyloid …

One of the main research topics related to Alzheimer's disease is the aggregation of the
amyloid-β peptide, which was shown to follow different pathways for the two major alloforms …