Akt1 is implicated in cell metabolism, survival migration, and gene expression; however, little
is known about the role of specific Akt isoforms during inflammation in vivo. Thus, we directly …

Sepsis induces extensive death of lymphocytes that may contribute to the
immunosuppression and mortality of the disorder. The serine/threonine kinase Akt is a key …

Protein kinase B (Akt1) holds a central role for cellular growth, development, and survival,
but the cellular pathways of Akt1 that prevent inflammatory demise in the vascular system …

In neutrophils, the phosphoinositide 3-kinase/Akt signaling cascade is involved in migration,
degranulation, and O2− production. However, it is unclear whether the Akt kinase isoforms …

Akt, or protein kinase B, is a multifunctional serine-threonine protein kinase implicated in a
diverse range of cellular functions including cell metabolism, survival, migration, and gene …

Background—In hypertension, reduced nitric oxide production and blunted endothelial
vasorelaxation are observed. It was recently reported that AKT phosphorylates and activates …

Akt, a serine-threonine protein kinase, exists as three isoforms. The Akt signaling pathway
controls multiple cellular functions in the cardiovascular system, and the atheroprotective …

Akt (protein kinase B) is a serine/threonine protein kinase that regulates cell metabolism,
survival and proliferation. Recent studies of the role of Akt in phagocytosis, intracellular …

Akt kinases control essential cellular functions, including proliferation, apoptosis,
metabolism and transcription, and have been proposed as promising targets for treatment of …

Previous in vivo and in vitro studies have shown that Akt1 serves as a crucial regulator of
vascular maturation, extracellular matrix composition, and angiogenesis in tumors. Hence …