Purpose This study was designed to examine the aggressive features of BRAF-positive
papillary thyroid cancer (PTC) and association with age. Methods We compared the …

Background: Given the increasing incidence of papillary thyroid carcinoma despite stable
disease-specific mortality rates, the potential for the disease to reoccur is a key outcome to …

Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85–
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …

Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

The role of telomerase reverse transcriptase (TERT) gene promoter mutations in the
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …

A high prevalence of the BRAF V600E somatic mutation was recently reported in several
series of papillary thyroid carcinomas (PTC). This mutation appears to be particularly …

Clinicians have long sought to characterize biological markers of neoplasia as objective
indicators of tumor presence, pathogenicity, and prognosis. Armed with data that correlate …

Objective Genetic alterations in four oncogenes, namely RAS point mutations, RET
rearrangements (RET/PTC), NTRK1 rearrangements (TRK) and BRAF point mutations have …

The prognostic value of the BRAFV600E mutation, resulting in poor clinical outcomes of
papillary thyroid carcinoma, has been generally confirmed. However, the association of …

Background Clinical outcome of papillary thyroid carcinoma (PTC) in children differs
significantly from that of adults. There is no clear explanation of this difference although …