[HTML][HTML] Single-cell RNA sequencing reveals spatiotemporal heterogeneity and malignant progression in pancreatic neuroendocrine tumor
Y Zhou, S Liu, C Liu, J Yang, Q Lin… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Aims: Using Single-cell RNA sequencing (scRNA-seq), we explored the spatiotemporal
heterogeneity of pancreatic neuroendocrine tumors (pNETs) and the underlying mechanism …
heterogeneity of pancreatic neuroendocrine tumors (pNETs) and the underlying mechanism …
Molecular characterization of metastatic pancreatic neuroendocrine tumors (PNETs) using whole-genome and transcriptome sequencing
H Wong, KC Yang, Y Shen… - Molecular …, 2018 - molecularcasestudies.cshlp.org
Pancreatic neuroendocrine tumors (PNETs) are a genomically and clinically heterogeneous
group of pancreatic neoplasms often diagnosed with distant metastases. Recurrent somatic …
group of pancreatic neoplasms often diagnosed with distant metastases. Recurrent somatic …
[HTML][HTML] Proteotranscriptomic classification and characterization of pancreatic neuroendocrine neoplasms
Pancreatic neuroendocrine neoplasms (PNENs) are biologically and clinically
heterogeneous. Here, we use a multi-omics approach to uncover the molecular factors …
heterogeneous. Here, we use a multi-omics approach to uncover the molecular factors …
[HTML][HTML] Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …
whose causation is only partly understood. An increasing number of studies have uncovered …
Real-time genomic characterization of metastatic pancreatic neuroendocrine tumors has prognostic implications and identifies potential germline actionability
Purpose We assessed the usefulness of real-time molecular profiling through next-
generation sequencing (NGS) in predicting the tumor biology of advanced pancreatic …
generation sequencing (NGS) in predicting the tumor biology of advanced pancreatic …
[HTML][HTML] Molecular biology of pancreatic neuroendocrine tumors: From mechanism to translation
X Shen, X Wang, X Lu, Y Zhao, W Guan - Frontiers in Oncology, 2022 - frontiersin.org
Pancreatic neuroendocrine tumors (pNETs) are a group of heterogeneous tumors originated
from progenitor cells. As these tumors are predominantly non-functional, most of them …
from progenitor cells. As these tumors are predominantly non-functional, most of them …
[HTML][HTML] Molecular signatures and their clinical utility in pancreatic neuroendocrine tumors
PD Chatani, SK Agarwal, SM Sadowski - Frontiers in Endocrinology, 2021 - frontiersin.org
Pancreatic neuroendocrine tumors (PNETs) are classified based on their histologic
differentiation and proliferative indices, which have been used extensively to determine …
differentiation and proliferative indices, which have been used extensively to determine …
[HTML][HTML] Genomic landscape of pancreatic neuroendocrine tumors
N Gebauer, C Schmidt-Werthern… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To investigate the prognostic role of genomic stability and copy number alterations
(CNAs) pancreatic neuroendocrine tumors (PanNETs). METHODS: A high-resolution array …
(CNAs) pancreatic neuroendocrine tumors (PanNETs). METHODS: A high-resolution array …
Gene expression signatures identify novel therapeutics for metastatic pancreatic neuroendocrine tumors
Purpose: Pancreatic neuroendocrine tumors (pNETs) are uncommon malignancies noted for
their propensity to metastasize and comparatively favorable prognosis. Although both the …
their propensity to metastasize and comparatively favorable prognosis. Although both the …
CLEC3A, MMP7, and LCN2 as novel markers for predicting recurrence in resected G1 and G2 pancreatic neuroendocrine tumors
M Miki, T Oono, N Fujimori, T Takaoka… - Cancer …, 2019 - Wiley Online Library
Although the postoperative recurrence rate for pancreatic neuroendocrine tumors (PNETs) is
reported to be 13.5%‐30%, the paucity of valuable biomarkers to predict recurrence poses a …
reported to be 13.5%‐30%, the paucity of valuable biomarkers to predict recurrence poses a …
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