HTLV-1 Tax nucleocytoplasmic shuttling, interaction with the secretory pathway, extracellular signaling, and implications for neurologic disease
T Alefantis, P Jain, J Ahuja, K Mostoller… - Journal of biomedical …, 2005 - Springer
The human T cell leukemia virus type 1 (HTLV-1) oncoprotein Tax interacts with numerous
cellular pathways promoting both the survival and pathogenesis of the virus in the human …
cellular pathways promoting both the survival and pathogenesis of the virus in the human …
HTLV-1 oncoprotein Tax deregulates transcription of cellular genes through multiple mechanisms
M Yoshida - Journal of cancer research and clinical oncology, 1995 - Springer
Infection of a human retrovirus HTLV-1 induces adult T cell leukemia and a neurological
disease, HAM/TSP. Regulatory protein Tax of HTLV-1 is thought to contribute to the …
disease, HAM/TSP. Regulatory protein Tax of HTLV-1 is thought to contribute to the …
The HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6
S Legros, M Boxus, JS Gatot, C Van Lint, V Kruys… - Oncogene, 2011 - nature.com
Human T cell leukemia virus type-1 (HTLV-1) is the causative agent of two major diseases: a
rapidly fatal leukemia designated adult T-cell leukemia and a neurological degenerative …
rapidly fatal leukemia designated adult T-cell leukemia and a neurological degenerative …
Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.
WJ Grossman, JT Kimata, FH Wong… - Proceedings of the …, 1995 - National Acad Sciences
The human T-cell leukemia virus type I Tax protein trans-activates several cellular genes
implicated in T-cell replication and activation. To investigate its leukemogenic potential, Tax …
implicated in T-cell replication and activation. To investigate its leukemogenic potential, Tax …
Stable ubiquitination of human T-cell leukemia virus type 1 tax is required for proteasome binding
E Chiari, I Lamsoul, J Lodewick, C Chopin… - Journal of …, 2004 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) is the retrovirus responsible for adult T-cell
leukemia and HTLV-1-associated myelopathy. Adult T-cell leukemia development is mainly …
leukemia and HTLV-1-associated myelopathy. Adult T-cell leukemia development is mainly …
Abundant tax protein expression in CD4+ T cells infected with human T-cell lymphotropic virus type I (HTLV-I) is prevented by cytotoxic T lymphocytes
E Hanon, S Hall, GP Taylor, M Saito… - Blood, The Journal …, 2000 - ashpublications.org
The role of the cellular immune response in human T-cell leukemia virus type I (HTLV-I)
infection is not fully understood. A persistently activated cytotoxic T lymphocyte (CTL) …
infection is not fully understood. A persistently activated cytotoxic T lymphocyte (CTL) …
Requirement of the human T-cell leukemia virus (HTLV-1) tax-stimulated HIAP-1 gene for the survival of transformed lymphocytes
K Wäldele, K Silbermann, G Schneider, T Ruckes… - Blood, 2006 - ashpublications.org
The human T cell leukemia virus type 1 (HTLV-1) infection is causally linked with the
development of a severe and fatal lymphoproliferative disorder of CD4 T cells, the adult T …
development of a severe and fatal lymphoproliferative disorder of CD4 T cells, the adult T …
Genetic and epigenetic inactivation of tax gene in adult T‐cell leukemia cells
S Takeda, M Maeda, S Morikawa… - … journal of cancer, 2004 - Wiley Online Library
To clarify the status of tax gene, we analyzed human T‐cell leukemia virus type‐I (HTLV‐I)
associated cell lines and fresh adult T‐cell leukemia (ATL) cells. We compared 2 types of …
associated cell lines and fresh adult T‐cell leukemia (ATL) cells. We compared 2 types of …
Tax protein of HTLV-1 inhibits CBP/p300-mediated transcription by interfering with recruitment of CBP/p300 onto DNA element of E-box or p53 binding site
T Suzuki, M Uchida-Toita, M Yoshida - Oncogene, 1999 - nature.com
Tax protein of human T-cell leukemia virus type 1 (HTLV-1) is a potent transcriptional
regulator which can activate or repress specific cellular genes and has been proposed to …
regulator which can activate or repress specific cellular genes and has been proposed to …
Characterization of T cells immortalized by Tax1 of human T-cell leukemia virus type 1
T Akagi, H Ono, K Shimotohno - 1995 - ashpublications.org
Peripheral blood T cells were immortalized in vitro by introduction of the Tax1 gene of
human T-cell leukemia virus type 1 (HTLV-1) with a retroviral vector and were characterized …
human T-cell leukemia virus type 1 (HTLV-1) with a retroviral vector and were characterized …